Document Detail

Diagnostic value of the fast-FLAIR sequence in MR imaging of intracranial tumors.
MedLine Citation:
PMID:  10823626     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to quantify imaging characteristics of fast fluid-attenuated inversion recovery (FLAIR) sequence in brain tumors compared with T1-postcontrast- and T2-sequences. Fast-FLAIR-, T2 fast spin echo (FSE)-, and T1 SE postcontrast images of 74 patients with intracranial neoplasms were analyzed. Four neuroradiologists rated signal intensity and inhomogeneity of the tumor, rendering of cystic parts, demarcation of the tumor vs brain, of the tumor vs edema and of brain vs edema, as well as the presence of motion and of other artifacts. Data analysis was performed for histologically proven astrocytomas, glioblastomas, and meningiomas, for tumors with poor contrast enhancement, and for all patients pooled. Only for tumors with poor contrast enhancement (n = 12) did fast FLAIR provide additional information about the lesion. In these cases, signal intensity, demarcation of the tumor vs brain, and differentiation of the tumor vs edema were best using fast FLAIR. In all cases, rendering of the tumor's inner structure was poor. For all other tumor types, fast FLAIR did not give clinically relevant information, the only exception being a better demarcation of the edema from brain tissue. Artifacts rarely interfered with evaluation of fast-FLAIR images. Thus, fast FLAIR cannot replace T2-weighted series. It provides additional information only in tumors with poor contrast enhancement. It is helpful for defining the exact extent of the edema of any tumor but gives little information about their inner structure.
H W Husstedt; M Sickert; H Köstler; B Haubitz; H Becker
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European radiology     Volume:  10     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2000  
Date Detail:
Created Date:  2000-08-08     Completed Date:  2000-08-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  745-52     Citation Subset:  IM    
Abteilung Neuroradiologie, Medizinische Hochschule Hannover, Germany.
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MeSH Terms
Aged, 80 and over
Astrocytoma / diagnosis
Brain Edema / diagnosis
Brain Neoplasms / diagnosis*
Child, Preschool
Contrast Media
Glioblastoma / diagnosis
Image Enhancement / methods
Image Processing, Computer-Assisted / methods*
Magnetic Resonance Imaging / methods*
Meningioma / diagnosis
Middle Aged
Reg. No./Substance:
0/Contrast Media

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