| [Diagnostic value and clinical application of inner ear imaging after an intratympanic injection of gadolinium for Meniere's disease]. | |
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MedLine Citation:
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PMID: 22333142 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: To explore the positive visualization rate of endolymph space in Meniere's disease (MD) by three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI) and assess its diagnostic value of MD. METHODS: 3D-FLAIR MRI was performed at 24 h after an intratympanic injection of gadolinium diethylenetriamine penta-acetic acid in 51 MD patients. Then the examination results were summarized, analyzed and compared with those of vestibular evoked myogenic potential (VEMP) and glycerol tests. RESULTS: Gadolinium was found in perilymph inside inner ear. Furthermore the border between perilymph and endolymph was visible so that endolymphatic space was distinctly visualized on 3D-FLAIR MRI. Forty-nine (96.1%) patients demonstrated the signs of endolymphatic hydrops. Statistically significant differences existed between the results of 3D-FLAIR MRI and those of VEMP and glycerol tests (P < 0.05). No complication of tympanic membrane perforation or infection was observed. CONCLUSION: After an intratympanic injection of gadolinium, 3D-FLAIR MRI has a higher positive rate in MD patients. Though as an invasive procedure, it has fewer side effects and will become an important diagnostic tool for MD. |
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Authors:
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Xi Chen; Xiao-Dong Zhang; Xi Gu; Zhe-Ming Fang; Rong Zhang |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Zhonghua yi xue za zhi Volume: 91 ISSN: 0376-2491 ISO Abbreviation: Zhonghua Yi Xue Za Zhi Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2012-02-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7511141 Medline TA: Zhonghua Yi Xue Za Zhi Country: China |
Other Details:
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Languages: chi Pagination: 3246-9 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology, Head & Neck Surgery, First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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