| Diagnostic value of 16-slice multidetector computed tomography in symptomatic patients with suspected significant obstructive coronary artery disease. | |
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MedLine Citation:
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PMID: 17151814 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We investigated the diagnostic value and limitations of 16-slice multidetector computed tomography (MDCT) to detect significant obstructive coronary artery disease in symptomatic patients. A total of 43 symptomatic patients underwent conventional coronary angiography and 16-slice multidetector computed tomography for the detection of significant obstructive coronary artery disease. The diagnostic value and limitations of 16-slice multidetector computed tomography to detect significant coronary stenoses were determined by analyzing all coronary arteries and proximal segments, both including and excluding unevaluable segments. Analysis of all 592 coronary artery segments demonstrated moderate sensitivity (67%) and positive predictive value (69%), with a high specificity (95%) and negative predictive value (94%) for the detection of significant coronary artery stenoses. When the unevaluable segments had been excluded, with the analysis of all evaluable segments, proximal segments, and evaluable proximal segments, sensitivity increased (71%, 77%, and 83%, respectively), and high specificity (95%, 96%, and 96%, respectively) and negative predictive value (95%) were maintained. When we repeated the analysis taking only the patients into account, 16-slice MDCT correctly diagnosed 88% of all patients but a moderate negative predictive value (63%) was obtained. Artifacts caused by cardiac motion were the most frequent reason for unevaluable segments. Calcification was the leading cause of degraded image quality and incorrect diagnosis. Our results demonstrated that 16-slice MDCT has a moderate diagnostic value for the correct diagnosis of symptomatic patients with significant coronary artery disease. This result suggests that 16-slice MDCT may not be able to exclude significant coronary artery disease reliably in patients at high risk. |
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Authors:
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Nihan Erdogan; Nihal Akar; Murat Vural; Alper Canbay; Tugba Kayhan; Deniz Sahin; Erdem Diker; Sinan Aydogdu |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article Date: 2006-09-29 |
Journal Detail:
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Title: Heart and vessels Volume: 21 ISSN: 0910-8327 ISO Abbreviation: Heart Vessels Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-12-07 Completed Date: 2007-03-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8511258 Medline TA: Heart Vessels Country: Japan |
Other Details:
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Languages: eng Pagination: 278-84 Citation Subset: IM |
Affiliation:
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Department of Radiology, Med-Mar Diagnostic Center, Ankara, Turkey. nihaner71@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Coronary Angiography* Coronary Stenosis / radiography* Female Humans Male Middle Aged Predictive Value of Tests Reproducibility of Results Severity of Illness Index Tomography, X-Ray Computed / instrumentation, methods* Turkey |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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