Document Detail

Diagnostic usefulness of 18F-FDG PET/CT in the differentiation of pulmonary artery sarcoma and pulmonary embolism.
MedLine Citation:
PMID:  19680740     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to evaluate the usefulness of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in differentiating pulmonary artery sarcoma from pulmonary embolism. MATERIALS AND METHODS: We evaluated three patients with pulmonary artery sarcoma and 10 patients with proximal pulmonary embolism (6 men and 7 women, ranging in age from 35 to 94 years). All the patients had evidence of perfusion defects in their proximal pulmonary arteries on contrast-enhanced computed tomography (CT) scans performed prior to PET/CT. The maximum standardized uptake value (SUV(max)) of FDG uptake in all the lesions was measured using PET/CT. The location of lesions, background uptake or thrombi in the legs were evaluated in both groups as basic characteristics. RESULTS: The mean SUV(max) of the pulmonary artery sarcomas (7.63 +/- 2.21, n = 3) and the pulmonary embolisms (2.31 +/- 0.41, n = 10) were significantly different (P < 0.05). The mean times between the initial contrast-enhanced CT scan and PET/CT scan were similar in both groups (P = 0.7804). The differences in the locations in lesions between the three groups (right, left and bilateral) or background uptakes were not significant. CONCLUSION: FDG PET/CT could distinguish pulmonary artery sarcoma from pulmonary embolism based on the SUV(max) value.
Kimiteru Ito; Kazuo Kubota; Miyako Morooka; Yoshitaka Shida; Kanehiro Hasuo; Hisako Endo; Hiroshi Matsuda
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-13
Journal Detail:
Title:  Annals of nuclear medicine     Volume:  23     ISSN:  1864-6433     ISO Abbreviation:  Ann Nucl Med     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-18     Completed Date:  2009-11-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8913398     Medline TA:  Ann Nucl Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  671-6     Citation Subset:  IM    
Department of Nuclear Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama 350-1298, Japan.
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MeSH Terms
Aged, 80 and over
Diagnosis, Differential
Fluorodeoxyglucose F18 / diagnostic use*
Middle Aged
Positron-Emission Tomography
Pulmonary Artery / pathology,  radiography*,  radionuclide imaging*
Pulmonary Embolism / radiography*,  radionuclide imaging*
Sarcoma / radiography*,  radionuclide imaging*
Tomography, X-Ray Computed
Reg. No./Substance:
63503-12-8/Fluorodeoxyglucose F18

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