| Diagnostic tests for renal artery stenosis in patients suspected of having renovascular hypertension: a meta-analysis. | |
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MedLine Citation:
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PMID: 11560453 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To summarize and compare the validity of computed tomography angiography, magnetic resonance angiography, ultrasonography, captopril renal scintigraphy, and the captopril test for diagnosis of renal artery stenosis in patients suspected of having renovascular hypertension. DATA SOURCES: For each diagnostic modality, published studies were identified by MEDLINE literature searches. STUDY SELECTION: Original studies were selected if they met the following criteria: 1) suspicion of renovascular hypertension was the indication for the test; 2) intra-arterial x-ray angiography was used as the gold standard; 3) a cutoff point for a positive test result was explicitly defined; and 4) absolute numbers of true-positive, false-negative, true-negative, and false-positive results were available or could be derived from the presented data. DATA EXTRACTION: A standard form was used to extract relevant data. DATA SYNTHESIS: Data on the accuracy of the different diagnostic methods were analyzed and compared by constructing summary receiver-operating characteristic (ROC) curves and by computing areas under the summary ROC curves. RESULTS: Although accuracy varied greatly for all diagnostic modalities, summary ROC curves found that computed tomography angiography and gadolinium-enhanced, three-dimensional magnetic resonance angiography performed significantly better than the other diagnostic tests. CONCLUSIONS: Computed tomography angiography and gadolinium-enhanced three-dimensional magnetic resonance angiography seem to be preferred in patients referred for evaluation of renovascular hypertension. However, because few studies of these tests have been published, further research is recommended. |
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Authors:
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G B Vasbinder; P J Nelemans; A G Kessels; A A Kroon; P W de Leeuw; J M van Engelshoven |
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Publication Detail:
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Type: Comparative Study; Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Annals of internal medicine Volume: 135 ISSN: 0003-4819 ISO Abbreviation: Ann. Intern. Med. Publication Date: 2001 Sep |
Date Detail:
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Created Date: 2001-09-18 Completed Date: 2001-10-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372351 Medline TA: Ann Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 401-11 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Box 5800, University Hospital of Maastricht, NL-6202 AZ Maastricht, the Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiotensin-Converting Enzyme Inhibitors
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diagnostic use Captopril / diagnostic use Gadolinium / diagnostic use Humans Hypertension, Renovascular / complications*, diagnosis Linear Models Magnetic Resonance Angiography / methods ROC Curve Radioisotopes / diagnostic use Renal Artery Obstruction / diagnosis*, etiology*, radionuclide imaging, ultrasonography Reproducibility of Results Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Angiotensin-Converting Enzyme Inhibitors; 0/Radioisotopes; 62571-86-2/Captopril; 7440-54-2/Gadolinium |
| Comments/Corrections | |
Comment In:
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ACP J Club. 2002 Mar-Apr;136(2):69
[PMID:
11874294
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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