Document Detail

Diagnostic significance of indium-111 granulocyte scintigraphy in febrile patients.
MedLine Citation:
PMID:  3806219     Owner:  NLM     Status:  MEDLINE    
Sixty-eight patients with fever of unknown origin, 32 patients with postoperative fever, and 26 patients with therapy-resistant fever after bacteremia were investigated with [111In] granulocyte scintigraphy for the detection of abscesses. The results showed that the value of [111In]granulocyte scintigraphy in the detection of infectious foci vary in these three types of febrile conditions. The overall sensitivity and specificity were 86.5% and 87.8%, respectively. We observed, however, a relatively low predictive value of a positive result in the fever of unknown origin group (73.1%), and also a low predictive value of a negative result in the bacteremia group (66.7%). The C-reactive protein (CRP) levels in patients with a true-positive scintigram were significantly (p less than 0.001) higher than in patients with a true-negative scintigram. There was also a significant positive correlation (p less than 0.01) between the serum CRP concentration and the intensity of the granulocyte accumulations. There was no correlation between the peripheral leukocyte count or the erythrocyte sedimentation rate (ESR) and the intensity of the granulocyte uptake. Therefore CRP, but not the leukocyte count or ESR, appears useful for selecting the patients who benefit most from granulocyte scintigraphy.
M T Syrjälä; V Valtonen; K Liewendahl; G Myllylä
Related Documents :
19411389 - Erythrocyte sedimentation rate, c-reactive protein, or rheumatoid factor are normal at ...
3806219 - Diagnostic significance of indium-111 granulocyte scintigraphy in febrile patients.
18784579 - Correlation between il-6 levels and the systemic inflammatory response score: can an il...
16210709 - Inflammation is associated with increased energy expenditure in patients with chronic k...
20955949 - Inflammatory cytokines in saliva: early signs of metabolic disorders in chronic kidney ...
11274279 - C-reactive protein and chronic chlamydia pneumoniae infection--long-term predictors for...
23563619 - Right atrial tachycardias related to regions of low-voltage myocardium in patients with...
12220699 - Interleukin-10 promoter polymorphisms in patients with multiple sclerosis.
7353189 - Cimetidine premedication in elective caesarean section.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of nuclear medicine : official publication, Society of Nuclear Medicine     Volume:  28     ISSN:  0161-5505     ISO Abbreviation:  J. Nucl. Med.     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-02-26     Completed Date:  1987-02-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0217410     Medline TA:  J Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  155-60     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Bacterial Infections / radionuclide imaging*
Blood Sedimentation
C-Reactive Protein / analysis
Fever / etiology,  radionuclide imaging*
Fever of Unknown Origin / radionuclide imaging
Indium / diagnostic use*
Leukocyte Count
Middle Aged
Postoperative Complications / radionuclide imaging
Predictive Value of Tests
Radioisotopes / diagnostic use*
Sepsis / radionuclide imaging
Reg. No./Substance:
0/Radioisotopes; 7440-74-6/Indium; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Clipping of an AVM arterial feeder through a burr hole prior to radical surgery. Technical note.
Next Document:  Scintigraphic monitoring of mucociliary tracheo-bronchial clearance of technetium-99m macroaggregate...