| Diagnostic and prognostic value of cardiac magnetic resonance imaging in assessing myocardial viability. | |
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MedLine Citation:
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PMID: 18690157 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Assessment of viability is pivotal to the prognosis of patients with chronic coronary artery disease (CAD) and left ventricular dysfunction. Patients with viable myocardium have a better prognosis with revascularization; however, patients with nonviable myocardium have worse outcomes with higher perioperative morbidity and mortality subsequent to revascularization. Cardiac magnetic resonance (CMR) imaging not only is the current reference standard technique in measuring cardiac chamber size and function and myocardial mass and volume but also provides spatially registered 2- or 3-dimensional data sets in myocardial perfusion and myocardial contrast enhancement in the same imaging session. Late gadolinium enhancement by CMR is the best current technique in discriminating myocardial scar versus viable myocardium. An extensive body of preclinical evidence has validated the detection and characterization of the morphology of infarcted tissue. In clinical studies, infarct characteristics by CMR has demonstrated a strong clinical utility in the prediction of left ventricular functional recovery and patient prognosis. In this paper, we aim to review the current CMR techniques in characterizing the spectrum of myocardial changes because of CAD, in the prediction of myocardial viability, and the current evidence of CMR's role in patient prognosis. In addition, we will also review the current literature comparing the clinical utility of CMR with other established imaging modalities in the assessment of CAD. |
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Authors:
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Raymond Y Kwong; Hema Korlakunta |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: Topics in magnetic resonance imaging : TMRI Volume: 19 ISSN: 1536-1004 ISO Abbreviation: Top Magn Reson Imaging Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-08-11 Completed Date: 2008-10-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8913523 Medline TA: Top Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 15-24 Citation Subset: IM |
Affiliation:
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Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA. rykwong@partners.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cell Survival Coronary Disease / diagnosis, therapy Female Gadolinium DTPA / diagnostic use* Humans Image Enhancement / methods* Image Processing, Computer-Assisted Magnetic Resonance Imaging / methods Magnetic Resonance Imaging, Cine / methods* Male Middle Aged Myocardial Infarction / diagnosis*, therapy Myocardial Ischemia / diagnosis, therapy Myocardial Reperfusion / methods Myocardium / pathology* Positron-Emission Tomography / methods Prognosis Sensitivity and Specificity Tissue Survival / physiology* Tomography, Emission-Computed, Single-Photon / methods Ventricular Remodeling / physiology |
| Chemical | |
Reg. No./Substance:
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80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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