Document Detail

Diagnostic performances of shear wave elastography: which parameter to use in differential diagnosis of solid breast masses?
MedLine Citation:
PMID:  23423637     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate which shear wave elastography (SWE) parameter proves most accurate in the differential diagnosis of solid breast masses.
METHODS: One hundred and fifty-six breast lesions in 139 consecutive women (mean age: 43.54 ± 9.94 years, range 21-88 years), who had been scheduled for ultrasound-guided breast biopsy, were included. Conventional ultrasound and SWE were performed in all women before biopsy procedures. Ultrasound BI-RADS final assessment and SWE parameters were recorded. Diagnostic performance of each SWE parameter was calculated and compared with those obtained when applying cut-off values of previously published data. Performance of conventional ultrasound and ultrasound combined with each parameter was also compared.
RESULTS: Of the 156 breast masses, 120 (76.9 %) were benign and 36 (23.1 %) malignant. Maximum stiffness (Emax) with a cut-off of 82.3 kPa had the highest area under the receiver operating characteristics curve (Az) value compared with other SWE parameters, 0.860 (sensitivity 88.9 %, specificity 77.5 %, accuracy 80.1 %). Az values of conventional ultrasound combined with each SWE parameter showed lower (but not significantly) values than with conventional ultrasound alone.
CONCLUSIONS: Maximum stiffness (82.3 kPa) provided the best diagnostic performance. However the overall diagnostic performance of ultrasound plus SWE was not significantly better than that of conventional ultrasound alone.
KEY POINTS: • SWE offers new information over and above conventional breast ultrasound • Various SWE parameters were explored regarding distinction between benign and malignant lesions • An elasticity of 82.3 kPa appears optimal in differentiating solid breast masses • However, ultrasound plus SWE was not significantly better than conventional ultrasound alone.
Eun Jung Lee; Hae Kyoung Jung; Kyung Hee Ko; Jong Tae Lee; Jung Hyun Yoon
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Publication Detail:
Type:  Journal Article     Date:  2013-02-20
Journal Detail:
Title:  European radiology     Volume:  23     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-06     Completed Date:  2014-01-22     Revised Date:  2014-08-26    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1803-11     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Breast / pathology
Breast Neoplasms / diagnosis*,  ultrasonography*
Diagnosis, Differential
Elasticity Imaging Techniques / methods*
Image Processing, Computer-Assisted
Middle Aged
ROC Curve
Reproducibility of Results
Sensitivity and Specificity
Ultrasonography, Mammary / methods*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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