| Diagnostic performances of shear wave elastography: which parameter to use in differential diagnosis of solid breast masses? | |
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MedLine Citation:
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PMID: 23423637 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate which shear wave elastography (SWE) parameter proves most accurate in the differential diagnosis of solid breast masses. METHODS: One hundred and fifty-six breast lesions in 139 consecutive women (mean age: 43.54 ± 9.94 years, range 21-88 years), who had been scheduled for ultrasound-guided breast biopsy, were included. Conventional ultrasound and SWE were performed in all women before biopsy procedures. Ultrasound BI-RADS final assessment and SWE parameters were recorded. Diagnostic performance of each SWE parameter was calculated and compared with those obtained when applying cut-off values of previously published data. Performance of conventional ultrasound and ultrasound combined with each parameter was also compared. RESULTS: Of the 156 breast masses, 120 (76.9 %) were benign and 36 (23.1 %) malignant. Maximum stiffness (Emax) with a cut-off of 82.3 kPa had the highest area under the receiver operating characteristics curve (Az) value compared with other SWE parameters, 0.860 (sensitivity 88.9 %, specificity 77.5 %, accuracy 80.1 %). Az values of conventional ultrasound combined with each SWE parameter showed lower (but not significantly) values than with conventional ultrasound alone. CONCLUSIONS: Maximum stiffness (82.3 kPa) provided the best diagnostic performance. However the overall diagnostic performance of ultrasound plus SWE was not significantly better than that of conventional ultrasound alone. KEY POINTS : • SWE offers new information over and above conventional breast ultrasound • Various SWE parameters were explored regarding distinction between benign and malignant lesions • An elasticity of 82.3 kPa appears optimal in differentiating solid breast masses • However, ultrasound plus SWE was not significantly better than conventional ultrasound alone. |
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Authors:
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Eun Jung Lee; Hae Kyoung Jung; Kyung Hee Ko; Jong Tae Lee; Jung Hyun Yoon |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-2-20 |
Journal Detail:
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Title: European radiology Volume: - ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-2-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology, CHA Bundang Medical Center, CHA University, School of Medicine, 351 Yatapdong, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-712, Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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