Document Detail

Diagnostic performance of duplex ultrasonography in the detection of high grade internal carotid artery stenosis.
MedLine Citation:
PMID:  12093067     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: to establish on a national basis whether the diagnostic accuracy of carotid duplex justifies carotid surgery without preoperative angiography. DESIGN: prospective national multicentre study with 10 participating university and county hospitals. MATERIAL AND METHODS: one hundred and thirty-four patients, aged 69+/-9 years, were subjected to routine carotid duplex ultrasonography and angiography. The influence of relevant factors on the relation between ultrasonographic and angiographic variables was evaluated using multiple regression analysis. The capacity of carotid ultrasonography to detect internal carotid artery (ICA) stenosis > or =80% was assessed by receiver operating characteristic analysis. RESULTS: the correlation between peak systolic velocity in ICA (PSV(ICA)) and the angiographic degree of stenosis was strong and significantly influenced only by the applied Doppler angle. Accordingly, the optimal PSV(ICA) cutpoint values for the diagnosis of ICA stenosis > or =80% (ECST method) differed substantially (2.1 and 3.2 m/s) between the two considered angle ranges (0-49 degrees and 50-62 degrees ), the ability to identify high grade ICA stenosis being significantly better at small Doppler angles (0-49 degrees ). CONCLUSION: ultrasonographic duplex technique identifies high grade ICA stenosis with a high degree of accuracy, which can be further improved by the application of small Doppler angles and the use of angle range specific PSV(ICA) cut-off points.
T Jogestrand; M Lindqvist; J Nowak;
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery     Volume:  23     ISSN:  1078-5884     ISO Abbreviation:  Eur J Vasc Endovasc Surg     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-07-02     Completed Date:  2002-08-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9512728     Medline TA:  Eur J Vasc Endovasc Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  510-8     Citation Subset:  IM    
Copyright Information:
Copyright 2002 Elsevier Science Ltd.
Department of Clinical Physiology, Huddinge University Hospital, Stockholm, Sweden.
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MeSH Terms
Carotid Stenosis / radiography,  ultrasonography*
Middle Aged
Preoperative Care
Prospective Studies
Sensitivity and Specificity
Ultrasonography, Doppler, Duplex

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