| Diagnostic performance of CT, PET, side-by-side, and fused image interpretations for restaging of non-Hodgkin lymphoma. | |
| | |
MedLine Citation:
|
PMID: 17581717 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The purpose of this study was to compare the diagnostic performance of positron emission tomography (PET) alone, computed tomography (CT) alone, side-by-side reading, and fused images for restaging or follow-up of patients with malignant lymphoma. METHODS: Fifty patients with histologically confirmed non-Hodgkin lymphoma underwent an (18)fluoro-2-deoxyglucose (FDG)-PET scan, followed by a CT scan. CT alone, PET alone, side-by-side reading, and fused images were interpreted separately and visually using a five-point grading scale for the following eight regions: cervical, supraclavicular, axillary, mediastinal, para-aortic to iliac, mesenteric, inguinal, and extra-nodal. Diagnostic accuracy was compared on the basis of the final diagnoses determined by histological confirmation and/or clinical course. RESULTS: For all regions combined, the interpretation of PET alone (sensitivity = 86.1%, specificity = 99.4%, accuracy = 91.0%), side-by-side reading (96.0%, 99.4%, 98.9%), and fused images (98.0%, 99.4%, 99.2%) yielded significantly higher diagnostic performance than that of CT alone (59.4%, 96.1%, 91.0%; P < 0.001). The cervical, supraclavicular, and extra-nodal regions were more accurately diagnosed with PET (P < 0.05), whereas the para-aortic to iliac regions were diagnosed more accurately with side-by-side reading and fused images than with CT alone or PET alone (P < 0.05). CONCLUSIONS: Although fused images are clinically valuable, side-by-side reading showed equivalent performance, whereas the interpretation of PET alone yielded reasonably high diagnostic performance for restaging or follow-up of patients with malignant lymphoma. |
| | |
Authors:
|
Munenobu Nogami; Yuji Nakamoto; Setsu Sakamoto; Kazuto Fukushima; Tomohisa Okada; Tsuneo Saga; Tatsuya Higashi; Michio Senda; Toshimitsu Matsui; Kazuro Sugimura |
Related Documents
:
|
15471827 - Pet/ct using 18f-fdg in suspected lung cancer recurrence: diagnostic value and impact o... 19205017 - Identification of distant metastases with pet-ct in patients with suspected recurrent h... 17701257 - Clinical practice guidelines for the utilization of positron emission tomography/comput... 22578877 - Quantification of synovitis in the cranio-cervical region: dynamic contrast enhanced an... 1392687 - Incidence of positive aspiration in the gow-gates mandibular block. 9486067 - The value of indium-111-labelled leucocyte imaging and ultrasonography in the investiga... |
Publication Detail:
|
Type: Journal Article Date: 2007-06-25 |
Journal Detail:
|
Title: Annals of nuclear medicine Volume: 21 ISSN: 0914-7187 ISO Abbreviation: Ann Nucl Med Publication Date: 2007 Jun |
Date Detail:
|
Created Date: 2007-06-21 Completed Date: 2007-08-09 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8913398 Medline TA: Ann Nucl Med Country: Japan |
Other Details:
|
Languages: eng Pagination: 189-96 Citation Subset: IM |
Affiliation:
|
Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. aznogami@med.kobe-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Brain / pathology False Positive Reactions Female Humans Image Processing, Computer-Assisted / methods* Lymphoma, Non-Hodgkin / diagnosis*, pathology*, radiography Male Middle Aged Models, Statistical Neoplasm Staging / methods* Positron-Emission Tomography / methods* Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Novel noise reduction filter for improving visibility of early computed tomography signs of hyperacu...
Next Document: Improved accuracy of brain MRI/SPECT registration using a two-cluster SPECT normalization algorithm ...