| Diagnostic microspheres: an overview. | |
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MedLine Citation:
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PMID: 14979867 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Diagnostic methods have become increasingly complex and frequently involve the use of agents that must meet the same approval criteria as drugs. The search for diagnostic contrast agents has spread from X-ray to other imaging modalities, especially to magnetic resonance imaging (MRI) and ultrasound. A wide variety of methods have been used to develop microencapsulated agents, from liposomal entrapment to use of biodegradable polymers. Various scientific and technological advancements have been made in the research and development of diagnostic microspheres. Diagnostic microspheres can be used to understand the human body functions in both healthy and sick people. For example, they allow the detection of malignancies vs. benign tissue changes. Diagnostic microspheres give useful clinical information for various diseases, are very stable, and have proven efficacy in the quantitative measurement of blood flow to an organ. This review discusses various aspects of diagnostic microspheres, such as the choice of contrast agents and radioactive molecules, and their applications in blood flow measurements and organ imaging. |
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Authors:
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V R Sinha; V Goyal; J R Bhinge; B R Mittal; A Trehan |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Critical reviews in therapeutic drug carrier systems Volume: 20 ISSN: 0743-4863 ISO Abbreviation: Crit Rev Ther Drug Carrier Syst Publication Date: 2003 |
Date Detail:
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Created Date: 2004-02-24 Completed Date: 2004-07-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8511159 Medline TA: Crit Rev Ther Drug Carrier Syst Country: United States |
Other Details:
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Languages: eng Pagination: 431-60 Citation Subset: IM |
Affiliation:
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University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India. vr_sinha@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Contrast Media / administration & dosage* Delayed-Action Preparations / administration & dosage* Diagnostic Imaging / methods* Humans Microspheres Radioisotopes / administration & dosage* Technology, Pharmaceutical / methods |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Delayed-Action Preparations; 0/Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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