| Diagnostic impact of thallium scintigraphy and cardiac fluoroscopy when the exercise ECG is strongly positive. | |
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MedLine Citation:
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PMID: 6464963 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied 83 men, who had a chest pain syndrome, no prior history of myocardial infarction, and exercise-induced horizontal or downsloping ST segment depression greater than or equal to 0.2 mV. The 38 patients unable to complete Bruce stage II had a significant increased risk of coronary (0.97 vs 0.71) and multivessel (0.88 vs 0.61) disease (p less than 0.01) compared to the pretest risk; data obtained from exercise-reperfusion thallium scintigraphy and cardiac fluoroscopy did not alter the risk of coronary or multivessel disease. The 45 patients who had ST depression greater than or equal to 0.2 mV and a peak work capacity greater than or equal to Bruce stage III did not have a significant increased risk of coronary (0.76) or multivessel disease (0.44). When both exercise-reperfusion thallium scintigraphy and cardiac fluoroscopy were abnormal in this latter patient subgroup, the post-test risk of multivessel disease was increased from 0.44 to 0.82 (p less than 0.03); when both tests were normal, none of the patients had multivessel disease (p less than 0.03) and only 0.18 had coronary artery disease. Thus, cardiac fluoroscopy and exercise thallium scintigraphy increase the diagnostic content of the strongly positive exercise ECG, particularly in men who have a peak work capacity greater than or equal to Bruce stage III. |
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Authors:
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B R Chaitman; G Brevers; G Dupras; J Lesperance; M G Bourassa |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American heart journal Volume: 108 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1984 Aug |
Date Detail:
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Created Date: 1984-09-04 Completed Date: 1984-09-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 260-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angina Pectoris
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physiopathology,
radionuclide imaging Coronary Angiography Coronary Disease / diagnosis*, physiopathology, radiography, radionuclide imaging Electrocardiography* Exercise Test* Fluoroscopy* Heart / radiography, radionuclide imaging* Humans Male Middle Aged Pain Radioisotopes / diagnostic use* Thallium / diagnostic use* Thorax |
| Chemical | |
Reg. No./Substance:
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0/Radioisotopes; 7440-28-0/Thallium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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