| Diagnostic esophago-gastro-duodenoscopy (EGD) in patients with AIDS-related upper gastrointestinal abnormalities. | |
| | |
MedLine Citation:
|
PMID: 20214216 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND/AIMS: Gastrointestinal (GI) diseases are common among patients infected with human immunodeficiency virus (HIV), and may involve the entire GI tract. The aim of the article is to investigate the prevalence of various upper gastrointestinal abnormalities in patients with AIDS. METHODOLOGY: Diagnostic esophago-gastro-duodenoscopy (EGD) was performed in cohort of AIDS patients (total 186) including non-ART, mono and/or dual ART and HAART treated subgroups. Clinical presentation, level of immunosupression and presence of H. pylori infection was also considered. RESULTS: Endoscopic findings included normal (29), esophageal candidiasis (22), esophageal erosions (16), gastritis/duodenitis (135), gastric/duodenal ulcers (7), erosions (6) and infiltration/tumor in the stomach (5). Thirty-nine patients (20.4%) had opportunistic infections/tumors including candida esophagitis, CMV esophagitis, CMV gastritis, gastric non-Hodgkin's lymphoma (NHL) and gastric cryptosporidiosis. H. pylori infection was present in 25.8% of patients, and majority (89.6%) had chronic non-atrophic gastritis. These patients had a higher mean CD4 count compared with H. pylori negative patients (403.5 vs. 226.9 CD4+ cells/microL, p = 0.001). Patients who received HAART had significantly higher frequency of H. pylori infection then non-ART treated patients (p = 0.048). CONCLUSION: Candidiasis was the marker of advanced immunodeficiency, and H. pylori was more common in patients with higher CD4 cell counts on ART, which may suggest that this infection could be an unusual presentation of immune restoration inflammatory syndrome. |
| | |
Authors:
|
Milos Kora?; Branko Brmboli?; Dubravka Salemovi?; Jovan Ranin; Zorica Stojsi?; Djordje Jevtovi?; Jelena Nikoli? |
Related Documents
:
|
12167116 - Influences of helicobacter pylori on gastric angiogenesis and ulcer healing in mice. 16481966 - Treatment of helicobacter pylori infection. 16506396 - Helicobacter pylori infection prevents nocturnal gastric acid breakthrough. 11960066 - The incidence of helicobacter pylori infection is not increased among obese young indiv... 16917426 - Surgical critical care: fungal infections in surgical patients. 19154186 - The panton-valentine leukocidin vaccine protects mice against lung and skin infections ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Hepato-gastroenterology Volume: 56 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 2009 Nov-Dec |
Date Detail:
|
Created Date: 2010-03-10 Completed Date: 2010-03-25 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: Greece |
Other Details:
|
Languages: eng Pagination: 1675-8 Citation Subset: IM |
Affiliation:
|
Institute for Infectious & Tropical Diseases, University of Belgrade School of Medicine, Belgrade, Serbia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acquired Immunodeficiency Syndrome
/
complications* Adolescent Adult Aged Duodenoscopy* Esophagoscopy* Female Gastrointestinal Diseases / diagnosis*, microbiology Gastroscopy* Helicobacter Infections / epidemiology Helicobacter pylori Humans Male Middle Aged Prevalence Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Assessing the interstitial cells of Cajal, cells of enteric nervous system and neurotransmitters in ...
Next Document: Management of the total bowel diverticular disease.