Document Detail


Diagnostic efficacy of bone scintigraphy, magnetic resonance imaging, and positron emission tomography in bone metastases of myxoid liposarcoma.
MedLine Citation:
PMID:  18307201     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Myxoid liposarcomas (MLS) have a tendency to metastasize to unusual sites. We report an unusual case of bone metastases not detected by bone scan and neither by fluorodeoxyglucose positron emission tomography (PET-FDG) and successfully identified with magnetic resonance imaging (MRI) in a patient with metachronic MLS. Histopathological examination of the primary tumor evidenced a tumor with unfavorable prognostic markers, and the biopsy of an iliac bone lesion confirmed the diagnosis of metastatic disease. On histological grounds, the tumor showed features of a more differentiated neoplasm without foci of round cells or necrosis in the latter. MRI allowed the identification of disseminated disease compared to computed tomography (CT) and PET scans. Thus, because of the heterogeneous histological features of MLS and the biological behavior of the disease, a combined approach of FDGPET-CT and MRI, may allow a more accurate staging of soft tissue sarcomas.
Authors:
Carlos Conill; Xavier Setoain; Luis Colomo; Antonio Palacín; Andreu Combalia-Aleu; Jaime Pomés; Jordi Marruecos; Mauricio Vargas; Joan Maurel
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  27     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-05     Completed Date:  2008-06-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  625-8     Citation Subset:  IM    
Affiliation:
Department of Radiation Oncology, Musculoskeletal Oncology Unit, Institute of Hematology and Oncology, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. cconill@clinic.ub.es
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MeSH Terms
Descriptor/Qualifier:
Adult
Bone Neoplasms / diagnosis*,  secondary*
Fluorodeoxyglucose F18 / diagnostic use
Humans
Liposarcoma, Myxoid / diagnosis*,  pathology,  radionuclide imaging,  secondary*
Magnetic Resonance Imaging*
Male
Positron-Emission Tomography*
Soft Tissue Neoplasms / pathology*
Chemical
Reg. No./Substance:
63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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