Document Detail

Diagnostic dilemma: aspergillosis.
MedLine Citation:
PMID:  11273188     Owner:  NLM     Status:  MEDLINE    
Two cases of varied forms of Aspergillosis are reported who were being diagnosed and treated on different lines. One case, who was treated on lines of allergic bronchitis, had very high total eosinophil count and, fleeting pulmonary infiltrates over a period of 5 years along with history of cough, fever and weight loss. Aspergillus fumigatus was grown on sputum culture. On the background of a long standing history of bronchial asthma with evidence of peripheral as well as central eosinophilia, fleeting pulmonary infiltrates and A. fumigatus grown on sputum culture, we kept the diagnosis of Allergic Bronchopulmonary aspergillosis (ABPA) and put the patient on steroids and Itraconazole. Patient showed good response to therapy. Another case, a 50 year old male, presented to us with clinical picture of subacute myelitis. Being a known case of ABPA and on steroid therapy for long duration, we kept the diagnosis of invasive aspergillosis. Growth of Aspergillus fumigatus on sputum culture on three occasions and MR imaging of spine further supported our view. Aspergillosis of the lung do not have characteristic clinico-radiological features of permit the diagnosis and should be considered in the differential diagnosis of tuberculosis, pneumonia, bronchiectasis, lung abscess and bronchial asthma.
K Kothari; V Singh; R Sharma; R Khandelwal
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  48     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2001-03-01     Completed Date:  2001-04-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  India    
Other Details:
Languages:  eng     Pagination:  445-7     Citation Subset:  IM    
Department of Medicine, SMS Medical College, Jaipur.
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MeSH Terms
Aspergillosis / diagnosis*
Aspergillus fumigatus / isolation & purification*
Diagnosis, Differential
Lung Diseases, Fungal / diagnosis*
Middle Aged
Comment In:
J Assoc Physicians India. 2002 Oct;50:1336; author reply 1336-7   [PMID:  12568231 ]

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