Document Detail

Diagnostic accuracy of sonography versus magnetic resonance imaging for primary nasopharyngeal carcinoma.
MedLine Citation:
PMID:  24764338     Owner:  NLM     Status:  In-Data-Review    
Objectives- The purpose of this study was to prospectively assess the accuracy of sonography versus magnetic resonance imaging (MRI) for a diagnosis of primary nasopharyngeal carcinoma. Methods- A total of 150 patients suspected of having nasopharyngeal carcinoma underwent sonography and MRI. A diagnosis was obtained from an endoscopic biopsy that was collected from the suspected tumor or a normal nasopharynx. The diagnostic performance of sonography and MRI for nasopharyngeal carcinoma was evaluated by receiver operating characteristic curve analysis. The sensitivity and specificity of the two imaging methods were compared by the McNemar test. Results- Nasopharyngeal carcinoma was present in 71 of 150 patients (47.3%) and absent in 79 (52.7%). The sensitivity, specificity, and accuracy of sonography versus MRI for these cases were 90.1%, 84.8%, and 87.3% for sonography and 97.2%, 89.9%, and 93.3% for MRI, respectively. Both sonography and MRI had good diagnostic performance for nasopharyngeal carcinoma, with area under the curve values of 0.958 and 0.987, respectively. There was no significant difference in the rate of tumor detectability between sonography and MRI (P = .12), and the specificities of sonography and MRI were similar (P = .22). Conclusions- Both sonography and MRI are useful tools for clinical screening of nasopharyngeal carcinoma. However, sonography is less expensive and easier to perform. The results of this study also suggest that nasopharyngeal sonography could be used for the initial investigation of primary cancer in patients suspected of having nasopharyngeal carcinoma.
Yong Gao; Shang-Yong Zhu; Yi Dai; Bing-Feng Lu; Lu Lu
Related Documents :
22828388 - Intrinsically superparamagnetic fe-hydroxyapatite nanoparticles positively influence os...
18633448 - Treatment of avascular necrosis of the femoral head by hepatocyte growth factor-transge...
17721048 - Assessment of the anatomical relationship between the arcuate eminence and superior sem...
23835028 - Epirubicin loaded super paramagnetic iron oxide nanoparticle-aptamer bioconjugate for c...
21673228 - Acute chest pain investigation: utility of cardiac ct angiography in guiding troponin m...
17505088 - 3-point support mechanical steering system for high intensity focused ultrasound.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  33     ISSN:  1550-9613     ISO Abbreviation:  J Ultrasound Med     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-04-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  827-34     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Preoperative assessment of extrathyroidal extension of papillary thyroid carcinoma: comparison of 2-...
Next Document:  Three-dimensional contrast-enhanced sonography in the assessment of breast tumor angiogenesis: corre...