Document Detail


Diagnostic accuracy of postnatal ultrasound screening for urinary tract abnormalities.
MedLine Citation:
PMID:  19856001     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The study was aimed at (1) the determination of the incidence of abnormalities of the urinary tract in newborn infants detected by postnatal ultrasound screening, and (2) the evaluation of the diagnostic accuracy of postnatal ultrasound screening for detecting surgical urinary tract abnormalities. The prospective study was of full-term neonates born in the University Hospital of Olomouc in 2005-2008 who underwent renal ultrasound screening after 72 h of life. Significant findings were recorded. Subsequent diagnostic and therapeutic procedures were recorded and evaluated in a group of children with detected renal pelvic dilatation (RPD). (1) A total of 6,088 newborn infants was examined. The absolute and relative RPD incidence rates (anteroposterior diameter, APD) were as follows: 5-7 mm, 146 (2.4%); 7-10 mm, 70 (1.15%); 10-15 mm, 13 (0.21%), and 15 mm or more, 5 (0.08%). Of those, 16 children were operated on for abnormalities of the urinary tract, of which nine (56%) had been detected by prenatal screening. Other findings: six cases of unilateral renal agenesis, four cases of multicystic renal dysplasia, four of renal dystopia, one of polycystic kidney disease and one of renal hypoplasia. (2) A group of 224 children with postnatally detected RPD was examined, of whom 40 (17.9%) underwent voiding cystourethrography and/or scintigraphy and 16 (7.1%) were treated surgically. The receiver operating characteristic curves were analyzed, and the areas under the curves were calculated. Postnatal renal ultrasound screening is probably a suitable test for detecting significant urinary tract abnormalities.
Authors:
Jan H?lek; Hana Fl?gelov?; Kamila Mich?lkov?; Oldrich Smakal; Lubom?r Dubrava; Jana Zapletalov?; Vladim?r Janout
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-10-24
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  25     ISSN:  1432-198X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-21     Completed Date:  2010-04-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  281-7     Citation Subset:  IM    
Affiliation:
Department of Neonatology, University Hospital of Olomouc, IP Pavlova 6, Olomouc, Czech Republic. halek1@seznam.cz
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MeSH Terms
Descriptor/Qualifier:
Czech Republic / epidemiology
Dilatation, Pathologic / pathology,  ultrasonography
Female
Hospitals, University
Humans
Infant, Newborn
Kidney Pelvis / embryology*,  pathology*,  ultrasonography
Male
Predictive Value of Tests
Prospective Studies
ROC Curve
Reproducibility of Results
Ultrasonography
Urinary Tract* / abnormalities,  ultrasonography
Urogenital Abnormalities / diagnosis*,  embryology,  epidemiology
Urologic Diseases / diagnosis*,  embryology,  epidemiology

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