| Diagnostic accuracy of phase-inversion tissue harmonic imaging versus fundamental B-mode sonography in the evaluation of focal lesions of the kidney. | |
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MedLine Citation:
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PMID: 12760935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We compared phase-inversion tissue harmonic imaging with fundamental B-mode sonography in the evaluation of focal lesions of the kidney. SUBJECTS AND METHODS: For our prospective study, 114 patients underwent sonography of the kidneys in both modes, fundamental B-mode sonography and phase-inversion tissue harmonic imaging, in a randomly chosen scanning order. Imaging parameters were standardized. Sonographic diagnoses were made under real-time conditions by the examining radiologist. All sonographic diagnoses were compared with a diagnostic reference modality: contrast-enhanced CT, contrast-enhanced MR imaging, or histopathology. Three radiologists different from the examiners evaluated overall image quality, lesion conspicuity, and fluid-solid differentiation for both modalities using hard-copy images. RESULTS: In 70 patients, fundamental B-mode sonography as the first technique depicted 73 of 111 lesions 10 mm or larger and enabled 71 lesions to be correctly characterized (sensitivity, 65.8%; accuracy, 64.0%). As the first mode, phase-inversion tissue harmonic imaging depicted 57 of 65 focal lesions and enabled 54 lesions to be accurately classified in 44 patients (sensitivity, 87.7%; accuracy, 83.1%). The differences in sensitivity and accuracy were statistically significant (95% confidence interval). For overall image quality, lesion conspicuity, and fluid-solid differentiation phase-inversion harmonic imaging was superior to fundamental B-mode sonography (p < 0.0001). CONCLUSION: Phase-inversion tissue harmonic imaging is superior to fundamental B-mode sonography in the sonography of focal kidney lesions because phase-inversion tissue harmonic imaging has better overall image quality, lesion conspicuity, and fluid-solid differentiation. In six cases, phase-inversion tissue harmonic imaging added crucial diagnostic information that changed patient management. |
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Authors:
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Thorsten Schmidt; Christian Hohl; Patrick Haage; Marcus Blaum; Dagmar Honnef; Claudia Weibeta; Gundula Staatz; R W Günther |
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Publication Detail:
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Type: Comparative Study; Journal Article; Validation Studies |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 180 ISSN: 0361-803X ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2003 Jun |
Date Detail:
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Created Date: 2003-05-22 Completed Date: 2003-06-24 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 1639-47 Citation Subset: AIM; IM |
Affiliation:
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Department of Diagnostic Radiology, RWTH Aachen University Hospital, Pauwelsstr. 30, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Computer Systems Diagnosis, Differential Female Humans Kidney Neoplasms / pathology, radiography, ultrasonography* Magnetic Resonance Imaging Male Middle Aged Prospective Studies Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed Ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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