Document Detail

Diagnostic accuracy of the haemoglobin colour scale in neonates and young infants in resource-poor countries.
MedLine Citation:
PMID:  17716504     Owner:  NLM     Status:  MEDLINE    
Due to the insidious nature of infant anaemia, this disorder frequently remains undetected and untreated by health-care workers in resource-poor settings. We assessed the accuracy of a low-cost and simple diagnostic tool, the haemoglobin colour scale (HCS), in estimating haemoglobin (Hb) values in infants between zero and four months of age. In a rural hospital in Zambia, blood samples were analysed for Hb concentration by HCS and HemoCue method. Bland-Altman plots were used to express agreement between the two methods. The mean difference between HCS and HemoCue at birth (n = 94), two months (n = 87) and four months (n = 69) was 0.39, 0.20 and -0.11 g/dL, respectively. Limits of agreement were -2.39 to 1.51, -1.80 to 2.20 and -1.98 to 1.75 g/dL, respectively. Disagreement with HemoCue measurements of more than 2 g/dL was noted in only 4% of all blood samples. We conclude that the HCS provides Hb estimations in infants aged 0-4 months that are sufficiently accurate to improve timely recognition of anaemia in settings where there is no laboratory.
P F van Rheenen; L T T de Moor
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Tropical doctor     Volume:  37     ISSN:  0049-4755     ISO Abbreviation:  Trop Doct     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-08-24     Completed Date:  2007-10-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1301706     Medline TA:  Trop Doct     Country:  England    
Other Details:
Languages:  eng     Pagination:  158-61     Citation Subset:  IM    
Paediatric Gastroenterology, Department of Paediatrics, University Medical Center, Groningen, The Netherlands.
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MeSH Terms
Anemia, Neonatal / diagnosis*
Developing Countries*
Hemoglobinometry / methods*
Hemoglobins / analysis*
Infant, Newborn
Reference Standards
Reproducibility of Results
Reg. No./Substance:

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