Document Detail

Diagnostic accuracy of extended-length electrocardiogram in differentiating between athlete's heart and hypertrophic cardiomyopathy.
MedLine Citation:
PMID:  19577245     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Standard 12-lead electrocardiogram (ECG) has several limitations in solving the differential diagnosis between physiologic left ventricular hypertrophy (PLVH) and hypertrophic cardiomyopathy (HCM), given the high rate of false-positive results in athletes. The aim of this study was to assess the usefulness of several arrhythmic risk indexes in differentiating PLVH from HCM. METHODS: A multiparametric ECG analysis (extended-length ECG) was performed on 30 male athletes with PLVH and 30 male patients with HCM, with homogeneous age distribution. RESULTS: The combination of 4 extended-length ECG variables, namely, corrected QT interval (Bazett), QT dispersion, mean resting heart rate, and low-amplitude signal duration at 25 Hz (low-amplitude signal duration at the end of filtered QRS) displayed remarkable diagnostic accuracy (area under receiver operating characteristic curve, 94%). The same accuracy was obtained replacing QT dispersion with T-wave complexity index. CONCLUSIONS: Extended-length ECG can be considered an effective, low-cost, and low time-consuming clinical tool for distinguishing between PLVH and HCM.
Luigi Caselli; Giorgio Galanti; Luigi Padeletti; Michele Nieri; Franco Cecchi; Franco Cipollini; Massimo Baldi; Laura Perrotta; Simone Vignini; Antonio Michelucci
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-07-03
Journal Detail:
Title:  Journal of electrocardiology     Volume:  42     ISSN:  1532-8430     ISO Abbreviation:  J Electrocardiol     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-10-26     Completed Date:  2010-01-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  636-41     Citation Subset:  IM    
Sports Medicine Department, Careggi Hospital, University of Florence, Viale Morgagni 85, Florence, Italy.
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MeSH Terms
Cardiomyopathy, Hypertrophic / diagnosis*
Diagnosis, Computer-Assisted / methods*
Diagnosis, Differential
Electrocardiography / methods*
Hypertrophy, Left Ventricular / diagnosis*
Middle Aged
Reproducibility of Results
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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