Document Detail


Diagnostic accuracy of CT angiography in acute gastrointestinal bleeding.
MedLine Citation:
PMID:  18811756     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of the study was to carry out a systematic review determining the accuracy of CT angiography in the diagnosis of acute gastrointestinal bleeding. A search of published work in Medline and manual searching of reference lists of articles was conducted. Studies were included if they compared CT angiography to a reference standard of upper gastrointestinal endoscopy, colonoscopy, angiography or surgery in the diagnosis of acute gastrointestinal bleeding. Eight published studies evaluating 129 patients were included. Data were used to form 2 x 2 tables. Computed tomography angiography showed pooled sensitivity of 86% (95% confidence interval 78-92%) and specificity of 95% (95% confidence interval 76-100%), without showing significant heterogeneity (chi(2) = 3.5, P = 0.6) and (chi(2) = 5.4, P = 0.6), respectively. Summary receiver operating characteristic analysis showed an area under the curve of 0.93. Computed tomography angiography is accurate in the diagnosis of acute gastrointestinal bleeding and can show the precise location and aetiology of bleeding, thereby directing further management. Strong recommendations for use of CT cannot be made from this review because of the methodological limitations and further large prospective studies are needed to define the role of CT in acute gastrointestinal bleeding.
Authors:
A E Chua; L J Ridley
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Publication Detail:
Type:  Journal Article; Meta-Analysis    
Journal Detail:
Title:  Journal of medical imaging and radiation oncology     Volume:  52     ISSN:  1754-9485     ISO Abbreviation:  -     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-09-24     Completed Date:  2009-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101469340     Medline TA:  J Med Imaging Radiat Oncol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  333-8     Citation Subset:  IM    
Affiliation:
Department of PET registrar, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia. chua.angela@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Angiography / statistics & numerical data*
Female
Gastrointestinal Hemorrhage / epidemiology*,  radiography*
Humans
Male
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / statistics & numerical data*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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