Document Detail

Diagnostic accuracy of 16- versus 64-slice multidetector computed tomography angiography in the evaluation of coronary artery bypass grafts: a comparative study.
MedLine Citation:
PMID:  22833506     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Multidetector computed tomography (MDCT) angiography, which is used for native coronary vessels and bypass graft (CABG) imaging is a non-invasive test. Here, we aimed to compare the diagnostic accuracy of 16- and 64-slice MDCT for graft patency and stenosis.
METHODS: A total of 129 consecutive patients with CABG who underwent both MDCT (58 patients with 16-slice, 71 patients with 64-slice) and invasive angiography were included. Median time interval between the two procedures was 12 days (range 3-28 days). Bypass grafts were evaluated concerning patency and presence of stenosis ≥ 50%. Both 16- and 64-slice MDCT results were compared with invasive angiography.
RESULTS: Overall diagnostic accuracy for the detection of graft patency was 95% for 64-slice vs 92% for 16-slice MDCT. By analyzing the 173 grafts by 64-slice vs 153 grafts by 16-slice MDCT that could be evaluated, sensitivity, specificity, positive predictive values (PPV) and negative predictive values (NPV) of the MDCT for visualization of graft patency were 90, 98, 90 and 98% vs 87, 97, 94 and 93%, respectively. The accuracy of MDCT for the detection of significant graft stenosis was relatively low (sensitivity, specificity, PPV and NPV were 67, 98.6, 50 and 98.6% with 16-slice vs 80, 98.1, 72.7 and 98.7% with 64-slice).
CONCLUSIONS: This study showed that the 16-slice has a diagnostic accuracy comparable with the 64-slice system for graft patency and can still be used for this purpose if newer systems with improved performance are not available on-site. On the other hand, by the virtue of better image quality, the 64-slice MDCT demonstrates significant graft lesions with higher sensitivity.
Levent Şahiner; Ugur Canpolat; Kudret Aytemir; Tuncay Hazirolan; Hikmet Yorgun; Ergün Bariş Kaya; Ali Oto
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2012-07-25
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  15     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-26     Completed Date:  2013-04-11     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  847-53     Citation Subset:  IM    
Department of Cardiology, Hacettepe University, Ankara, Turkey.
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MeSH Terms
Chi-Square Distribution
Constriction, Pathologic
Coronary Angiography / methods*
Coronary Artery Bypass*
Coronary Restenosis / etiology,  physiopathology,  radiography*
Graft Occlusion, Vascular / etiology,  physiopathology,  radiography*
Middle Aged
Multidetector Computed Tomography*
Predictive Value of Tests
Retrospective Studies
Sensitivity and Specificity
Severity of Illness Index
Time Factors
Treatment Outcome
Vascular Patency
Comment In:
Interact Cardiovasc Thorac Surg. 2012 Nov;15(5):853   [PMID:  23100553 ]

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