Document Detail

The Diagnostic Utility of Cardiac Biomarkers in Dialysis Patients.
MedLine Citation:
PMID:  22748194     Owner:  NLM     Status:  Publisher    
Mortality in dialysis patients remains high due to excessive cardiovascular disease burden from coronary artery disease, left ventricular hypertrophy, and heart failure. Thus, cardiovascular risk stratification is an important aspect in managing dialysis patients; it may enable early identification of high-risk patients to optimize therapeutic interventions that may ultimately lower their cardiovascular morbidity and mortality. In particular, serum cardiac biomarkers that are readily measured, inexpensive, reproducible with high sensitivity and specificity, may have potential for cardiovascular risk prediction and stratification. Cardiac troponin represents a highly sensitive and specific marker of myocardial damage and is a current gold standard test for diagnosing acute myocardial infarction in the general population. On the other hand, natriuretic peptides, released from the heart secondary to increased left ventricular wall stress, have emerged as a diagnostic marker for heart failure in the general population. These two biomarkers reflect unique pathology of the myocardium and are powerful prognostic markers in the dialysis population. This article reviews the diagnostic potentials of these two cardiac biomarkers and their clinical application in the dialysis population.
Angela Yee-Moon Wang; Christopher Wai-Kei Lam
Related Documents :
10535674 - Effects of adenosine and acadesine on interstitial nucleosides and myocardial stunning ...
6795344 - Difference in site and time course of coronary dilating effects of trapidil, nitroglyce...
10973014 - Intracoronary adenosine administered during percutaneous intervention in acute myocardi...
16214844 - Complement activation-related cardiac anaphylaxis in pigs: role of c5a anaphylatoxin an...
20595084 - Detection of (reversible) myocardial ischemic injury by means of electrical bioimpedance.
20360254 - Trb3 function in cardiac endoplasmic reticulum stress.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-2
Journal Detail:
Title:  Seminars in dialysis     Volume:  -     ISSN:  1525-139X     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8911629     Medline TA:  Semin Dial     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong Department of Chemical Pathology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pancreatic stone protein as an early biomarker predicting mortality in a prospective cohort of patie...
Next Document:  The use of electronic collars for training domestic dogs: estimated prevalence, reasons and risk fac...