| Diagnostic Testing for Diabetes Using HbA1c in the Abu Dhabi Population: Weqaya: the Abu Dhabi Cardiovascular Screening Program. | |
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MedLine Citation:
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PMID: 21926284 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVEThe validity of HbA(1c) as a population diagnostic tool was tested against oral glucose tolerance testing in Abu Dhabi nationals.RESEARCH DESIGN AND METHODSThe screening tool of HbA(1c) and random glucose was validated against the "gold standard" oral glucose tolerance test according to World Health Organization criteria.RESULTSThe HbA(1c) threshold of 6.4% provided the optimum balance between sensitivity (72.0%) and specificity (84.3%) with positive and negative predictive values of 47.9 and 93.7% and area under the receiver operating characteristics curve of 0.78. This threshold compares with a threshold of 6.5% recommended by the International Scientific Committee and American Diabetes Association and of 6.3% in a recent study in China.CONCLUSIONSThis study successfully validates the feasibility and threshold of HbA(1c) for diagnosis of diabetes at the population level in a Middle-Eastern population. This result is a major step in the fight to tackle the increasing burden of diabetes in the United Arab Emirates. |
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Authors:
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Cother Hajat; Oliver Harrison; Zaid Al Siksek |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-16 |
Journal Detail:
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Title: Diabetes care Volume: - ISSN: 1935-5548 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7805975 Medline TA: Diabetes Care Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Public Health and Research, Health Authority, Abu Dhabi, United Arab Emirates. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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