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Diagnostic Exercise Challenge Testing.
MedLine Citation:
PMID:  21915675     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This article reviews the diagnostic challenge methods-both exercise and surrogate-for diagnosis of exercise-induced bronchoconstriction (EIB) and EIB with known asthma. Indirect challenges that release the entire repertoire of mediators representative of EIB and asthma are more specific for diagnosis and are recommended over direct challenges such as methacholine challenge, which are sensitive but nonspecific. Self-reported history and empiric therapeutic trials are not adequate for diagnosis of EIB with or without known asthma. Objective pulmonary function documentation with bronchodilator reversibility or exercise or surrogate challenge are optimal for diagnosis of EIB or EIB with known asthma. Such objective pulmonary function documentation is optimal for the proper management and healthy lifestyle of the exercising athlete or individual.
Authors:
Christopher Randolph
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-14
Journal Detail:
Title:  Current allergy and asthma reports     Volume:  -     ISSN:  1534-6315     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101096440     Medline TA:  Curr Allergy Asthma Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Pediatrics/Medicine, Division of Allergy/Immunology Center for Allergy, Asthma, and Immunology, Yale University, 1389 West Main Street, Suite 205, Waterbury, CT, 06708, USA, ccrandolphmd@gmail.com.
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