Document Detail


Diagnostic Challenges and Pitfalls in MR Imaging with Hepatocyte-specific Contrast Agents.
MedLine Citation:
PMID:  21997981     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The use of gadolinium-based hepatocyte-specific contrast agents (HSCAs) has increased markedly since their introduction, and hepatocellular phase imaging performed with an HSCA is now a key part of the standard magnetic resonance (MR) imaging work-up for focal liver lesions. An understanding of the mechanisms of action of HSCAs helps ensure their effective use. The optimal delay for hepatocellular phase image acquisition differs between the two currently available HSCAs, gadoxetic acid and gadobenate dimeglumine, and MR imaging protocols must be adjusted accordingly. In addition, familiarity with typical and atypical appearances of benign and malignant focal liver lesions at HSCA-enhanced hepatocellular phase MR imaging, along with knowledge of the processes that are most likely to produce atypical appearances, is required to achieve optimal diagnostic accuracy.
Authors:
Mark D Goodwin; Julie E Dobson; Claude B Sirlin; Beng Ghee Lim; Damien L Stella
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiographics : a review publication of the Radiological Society of North America, Inc     Volume:  31     ISSN:  1527-1323     ISO Abbreviation:  Radiographics     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302501     Medline TA:  Radiographics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1547-68     Citation Subset:  IM    
Affiliation:
Department of Radiology, Austin Health, 145 Studley Road, Heidelberg, Melbourne, VIC 3084, Australia.
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