Document Detail

Diagnostic accuracy of contrast-enhanced magnetic resonance angiography and duplex ultrasound in patients with peripheral vascular disease.
MedLine Citation:
PMID:  20675318     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Noninvasive techniques such as duplex ultrasound (DU) and contrast-enhanced magnetic resonance angiography (CE-MRA) are valid alternatives in the preoperative evaluation of such patients. Our aim is to assess the diagnostic accuracy of CE-MRA and DU in patients with peripheral arterial disease (PAD).
METHODS: Forty consecutive patients underwent DU, hybrid CE-MRA, and digital subtraction angiography (DSA). Magnetic resonance angiography and DSA images were evaluated independently and in a blinded fashion. Every segment was graded as normal, stenosed less than 50%, stenosed more than 50%, or occluded.
RESULTS: There were 1720 segments for analysis. Duplex ultrasound depicting stenosis >50% demonstrated a sensitivity (S) 81.4%, specificity (E) 99%, positive predictive value (PPV) 96.2%, and negative predictive value (NPV) 94.8%. Occlusions showed S 90%, E 97%, PPV 98.1%, and NPV 88.4%. Magnetic resonance angiography depicting stenosis >50% demonstrated a S 91%, E 99%, PPV 96.7%, and NPV 97.6%. Occlusions showed S 95.4%, E 98%, PPV 98.4%, and NPV 94.7%.
CONCLUSION: Combined CE-MRA and DU is the first diagnostic approach in the preoperative assessment of PAD, leading to the use of DSA for selected cases.
Alicia Bueno; Francisco Acín; Cristina Cañibano; Jose L Fernandez-Casado; E Castillo
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-07-30
Journal Detail:
Title:  Vascular and endovascular surgery     Volume:  44     ISSN:  1938-9116     ISO Abbreviation:  Vasc Endovascular Surg     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-15     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136421     Medline TA:  Vasc Endovascular Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  576-85     Citation Subset:  IM    
Vascular Surgery Department, Hospital Universitario de Getafe, Madrid, Spain.
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MeSH Terms
Angiography, Digital Subtraction
Constriction, Pathologic
Contrast Media / diagnostic use*
Lower Extremity / blood supply*
Magnetic Resonance Angiography*
Meglumine / analogs & derivatives*,  diagnostic use
Observer Variation
Organometallic Compounds / diagnostic use*
Peripheral Arterial Disease / pathology*,  radiography,  ultrasonography*
Predictive Value of Tests
Prospective Studies
Reproducibility of Results
Sensitivity and Specificity
Severity of Illness Index
Ultrasonography, Doppler, Duplex*
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 113662-23-0/gadobenic acid; 6284-40-8/Meglumine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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