| Diagnostic accuracy of contrast-enhanced magnetic resonance angiography and duplex ultrasound in patients with peripheral vascular disease. | |
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MedLine Citation:
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PMID: 20675318 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Noninvasive techniques such as duplex ultrasound (DU) and contrast-enhanced magnetic resonance angiography (CE-MRA) are valid alternatives in the preoperative evaluation of such patients. Our aim is to assess the diagnostic accuracy of CE-MRA and DU in patients with peripheral arterial disease (PAD). METHODS: Forty consecutive patients underwent DU, hybrid CE-MRA, and digital subtraction angiography (DSA). Magnetic resonance angiography and DSA images were evaluated independently and in a blinded fashion. Every segment was graded as normal, stenosed less than 50%, stenosed more than 50%, or occluded. RESULTS: There were 1720 segments for analysis. Duplex ultrasound depicting stenosis >50% demonstrated a sensitivity (S) 81.4%, specificity (E) 99%, positive predictive value (PPV) 96.2%, and negative predictive value (NPV) 94.8%. Occlusions showed S 90%, E 97%, PPV 98.1%, and NPV 88.4%. Magnetic resonance angiography depicting stenosis >50% demonstrated a S 91%, E 99%, PPV 96.7%, and NPV 97.6%. Occlusions showed S 95.4%, E 98%, PPV 98.4%, and NPV 94.7%. CONCLUSION: Combined CE-MRA and DU is the first diagnostic approach in the preoperative assessment of PAD, leading to the use of DSA for selected cases. |
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Authors:
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Alicia Bueno; Francisco Acín; Cristina Cañibano; Jose L Fernandez-Casado; E Castillo |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2010-07-30 |
Journal Detail:
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Title: Vascular and endovascular surgery Volume: 44 ISSN: 1938-9116 ISO Abbreviation: Vasc Endovascular Surg Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-15 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136421 Medline TA: Vasc Endovascular Surg Country: United States |
Other Details:
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Languages: eng Pagination: 576-85 Citation Subset: IM |
Affiliation:
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Vascular Surgery Department, Hospital Universitario de Getafe, Madrid, Spain. abueno10@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angiography, Digital Subtraction Constriction, Pathologic Contrast Media / diagnostic use* Humans Lower Extremity / blood supply* Magnetic Resonance Angiography* Meglumine / analogs & derivatives*, diagnostic use Observer Variation Organometallic Compounds / diagnostic use* Peripheral Arterial Disease / pathology*, radiography, ultrasonography* Predictive Value of Tests Prospective Studies Reproducibility of Results Sensitivity and Specificity Severity of Illness Index Spain Ultrasonography, Doppler, Duplex* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 113662-23-0/gadobenic acid; 6284-40-8/Meglumine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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