| Diagnosis of unruptured intracranial aneurysms: 3T MR angiography versus 64-channel multi-detector row CT angiography. | |
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MedLine Citation:
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PMID: 19110511 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: We compared 3-dimensional time-of-flight magnetic resonance angiography (3D TOF MRA) using a 3-tesla (T) MR unit with 64-channel multi-detector row computed tomographic angiography (64-MDCTA) for detection and characterization of angiographically proven unruptured intracranial aneurysms. METHODS: Thirty-eight patients with 47 aneurysms and 8 patients without aneurysms underwent 3T, 3D TOF MRA; 64-MDCTA; and intra-arterial angiography. As a first study, 3 radiologists blinded to pertinent clinical information independently reviewed MRA and CTA images. We evaluated diagnostic accuracy using an alternative free-response receiver operating characteristic (AFROC) analysis and evaluated the sensitivity and specificity of each technique. Next, 2 radiologists used volume-rendering images generated from MRA or CTA data to evaluate the morphology of the 47 aneurysms detected, and MRA and CTA results were compared. Three-dimensional digital angiography (DA) images were used as the standard of reference. RESULTS: On the AFROC analysis, the value of the mean area under the AFROC curve (A(1)) was 0.91 for both modalities. Mean sensitivity of 89% and specificity of 76% for MRA were not significantly different from sensitivity of 87% and specificity of 79% for CTA. Therefore, when used to evaluate aneurysmal morphology, both modalities appear satisfactory for determining these vascular anomalies. CONCLUSION: Three-tesla, 3D TOF MRA and 64-MDCTA are excellent modalities with high diagnostic accuracy for evaluating unruptured intracranial aneurysms and no significant difference between them in diagnostic performance. |
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Authors:
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Yoshiyasu Hiratsuka; Hitoshi Miki; Ikuko Kiriyama; Keiichi Kikuchi; Shizue Takahashi; Ichiro Matsubara; Kazuhiko Sadamoto; Teruhito Mochizuki |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine Volume: 7 ISSN: 1347-3182 ISO Abbreviation: Magn Reson Med Sci Publication Date: 2008 |
Date Detail:
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Created Date: 2008-12-26 Completed Date: 2009-04-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101153368 Medline TA: Magn Reson Med Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 169-78 Citation Subset: IM |
Affiliation:
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Department of Radiology, Ehime University School of Medicine, Ehime, Japan. hirazka@m.ehime-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Area Under Curve Cerebral Angiography / methods* Female Humans Imaging, Three-Dimensional Intracranial Aneurysm / diagnosis*, pathology Magnetic Resonance Angiography / methods* Male Middle Aged Tomography, X-Ray Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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