Document Detail

Diagnosis and treatment of peripartum bleeding.
MedLine Citation:
PMID:  18783309     Owner:  NLM     Status:  MEDLINE    
Severe peripartum hemorrhage (PPH) contributes to maternal morbidity and mortality and is one of the most frequent emergencies in obstetrics, occurring at a prevalence of 0.5-5.0%. Detection of antepartum risk factors is essential in order to implement preventive measures. Proper training of obstetric staff and publication of recommendations and guidelines can effectively reduce the frequency of PPH and its resulting morbidity and mortality. Therefore, an interdisciplinary expert committee was formed, with members from Germany, Austria, and Switzerland, to summarize recent scientific findings. An up-to-date presentation of the importance of embolization and of the diagnosis of coagulopathy in PPH is provided. Furthermore, the committee recommends changes in the management of PPH including new surgical options and the off-label use of recombinant factor VIIa.
Wolfgang Henrich; Daniel Surbek; Franz Kainer; Oliver Grottke; Hartmut Hopp; Holger Kiesewetter; Jürgen Koscielny; Holger Maul; Dietmar Schlembach; Georg-Friedrich von Tempelhoff; Werner Rath
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Publication Detail:
Type:  Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  36     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2008  
Date Detail:
Created Date:  2008-11-07     Completed Date:  2009-02-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  467-78     Citation Subset:  IM    
Department of Obstetrics, Charité-University Medicine Berlin, 13353 Berlin, Germany.
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MeSH Terms
Blood Transfusion
Coagulants / therapeutic use
Disseminated Intravascular Coagulation / diagnosis,  epidemiology,  therapy
Embolization, Therapeutic
Factor VII / therapeutic use
Methylergonovine / therapeutic use
Oxytocics / therapeutic use
Oxytocin / therapeutic use
Placenta, Retained / epidemiology,  therapy
Postpartum Hemorrhage / diagnosis*,  epidemiology,  therapy*
Pregnancy Complications, Hematologic / epidemiology,  therapy
Prostaglandins / therapeutic use
Risk Factors
Suture Techniques
Uterine Inertia / epidemiology,  therapy
Uterine Rupture / epidemiology,  therapy
Uterus / pathology,  surgery
Reg. No./Substance:
0/Coagulants; 0/Oxytocics; 0/Prostaglandins; 113-42-8/Methylergonovine; 50-56-6/Oxytocin; 9001-25-6/Factor VII

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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