Document Detail


Diagnosis and treatment of colonic disease in AIDS.
MedLine Citation:
PMID:  9730938     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The colon is a frequent site of gastrointestinal complications in patients with HIV infection, and these colonic disorders increase in frequency as immunodeficiency worsens. The most common clinical manifestations of colonic disease in AIDS are diarrhea, lower gastrointestinal bleeding, and abdominal pain. Toxic megacolon, intussuseption, typhlitis, idiopathic colonic ulcer, and pneumatosis intestinalis also have been described. In the HIV-infected patient with preserved immunity, the most common cause of colitis is bacterial, but as the degree of immunodeficiency worsens, opportunistic pathogens (CMV, protozoa, mycobacteria, fungi) and neoplasms become more frequent. The frequent use of antibiotics, chemotherapeutic agents, and frequent hospitalization increase the susceptibility to cf2Clostridium difficule cf1colitis. Endoscopy plays an integral role in the management of many colonic disorders in AIDS.
Authors:
K E Mönkemüller; C M Wilcox
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Gastrointestinal endoscopy clinics of North America     Volume:  8     ISSN:  1052-5157     ISO Abbreviation:  Gastrointest. Endosc. Clin. N. Am.     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1999-02-22     Completed Date:  1999-02-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9202792     Medline TA:  Gastrointest Endosc Clin N Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  889-911     Citation Subset:  IM; X    
Affiliation:
Division of Gastroenterology and Hepatology, University of Alabama, Birmingham, Alabama 35294-0007, USA.
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / complications,  diagnosis,  therapy
Acquired Immunodeficiency Syndrome / complications*,  drug therapy
Adult
Anti-Infective Agents / therapeutic use*
Biopsy
Colectomy*
Colon / pathology,  radiography,  surgery
Colonic Diseases / complications,  diagnosis*,  therapy
Colonoscopy
Diagnosis, Differential
Follow-Up Studies
Humans
Immunosuppressive Agents / therapeutic use*
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 0/Immunosuppressive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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