Document Detail


Diagnosis and treatment of a cerebral infarct in a chimpanzee (Pan troglodytes).
MedLine Citation:
PMID:  15305516     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 29-yr-old chimpanzee (Pan troglodytes) presented after an acute onset of right facial and forearm paresis that progressed to paralysis within 24 hr, with subsequent development of right leg paresis. Magnetic resonance imaging (MRI) of the head revealed an abnormal region of increased signal intensity in the left frontal, parietal, and temporal cerebral hemispheres, corresponding to the vascular territory of the middle cerebral artery, with resultant compression of the left lateral ventricle. The findings were consistent with a cerebral infarct (stroke). MRI is the most sensitive test for early detection of cerebral changes due to ischemia and was essential in obtaining a diagnosis in this case. The chimpanzee responded well to treatment with long-term anticoagulant aspirin and a short, tapered course of prednisone and regained full gross motor function.
Authors:
Pilar H Fish; James W Carpenter; Susan Kraft
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians     Volume:  35     ISSN:  1042-7260     ISO Abbreviation:  J. Zoo Wildl. Med.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-08-12     Completed Date:  2004-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8915208     Medline TA:  J Zoo Wildl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  203-7     Citation Subset:  IM    
Affiliation:
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas 66506, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Ape Diseases / diagnosis*,  drug therapy*
Aspirin / therapeutic use*
Cerebral Infarction / diagnosis,  drug therapy,  veterinary*
Fibrinolytic Agents / therapeutic use*
Magnetic Resonance Imaging / veterinary
Male
Pan troglodytes*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Fibrinolytic Agents; 50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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