| Diagnosis of subclinical rickets. | |
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MedLine Citation:
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PMID: 7377839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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44 randomly selected infants under age one year with suspected lower respiratory infections were investigated for the presence of subclinical rickets. Seven infants had metaphyseal changes at the wrist compatible with a diagnosis of rickets and all of these infants had 25-hydroxy-vitamin D (25-OHD) concentrations less than 12 ng/ml. Serum calcium and phosphorus concentrations were normal in all 44 children. Alkaline phosphatase concentrations did not correlate with the presence of metaphyseal changes. The clinical presence of craniotabes or splaying and loss of definition of the anterior ends of the ribs on x-rays did not correlate with metaphyseal changes at the wrist or with 25-OHD concentrations. An x-ray of the wrist is essential to confirm the presence of subclinical rickets and the at-risk infant can be detected by measuring serum 25-OHD concentrations. |
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Authors:
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J M Pettifor; J M Isdale; J Sahakian; J D Hansen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of disease in childhood Volume: 55 ISSN: 1468-2044 ISO Abbreviation: Arch. Dis. Child. Publication Date: 1980 Feb |
Date Detail:
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Created Date: 1980-07-26 Completed Date: 1980-07-26 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0372434 Medline TA: Arch Dis Child Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 155-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Humans Hydroxycholecalciferols / blood Infant Male Ribs / radiography Rickets / blood, diagnosis*, radiography Ulna / radiography |
| Chemical | |
Reg. No./Substance:
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0/Hydroxycholecalciferols |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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