Document Detail

Diagnosis and staging of ovarian cancer.
MedLine Citation:
PMID:  6715399     Owner:  NLM     Status:  MEDLINE    
The diagnostic process in ovarian carcinoma is divided into the pre- and intraoperative procedures, examinations of tumor tissue, and follow-up. For preoperative diagnosis, the probability of a palpable adnexal mass being a malignant tumor should first be ascertained by sonography. This should be followed by an appropriate general examination, a search for tumor outside the abdominal cavity and in the liver parenchyma as well as by determination of markers. Intraoperative diagnosis determines the tumor stage and must be carried out all the more comprehensively when the ovarian carcinoma is more limited. Histologic subtype and degree of differentiation are in direct relation to the tumor stage, whereas the size of the primary tumor is often indirectly proportional to its extent. Besides the morphological analysis, the determination of possible chemoresistance and chemosensitivity, as well as further investigations on fresh tumor tissue are included in the tissue examination. Follow-up after a curative operation consists of gynecologic examination and Douglas lavages if tumor is still present in CT Scans and sonographs. To verify a relapse, laparoscopy can be used, but to ascertain a complete remission, a laparotomy is necessary.
A Pfleiderer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cancer research and clinical oncology     Volume:  107     ISSN:  0171-5216     ISO Abbreviation:  J. Cancer Res. Clin. Oncol.     Publication Date:  1984  
Date Detail:
Created Date:  1984-06-06     Completed Date:  1984-06-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7902060     Medline TA:  J Cancer Res Clin Oncol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  81-8     Citation Subset:  IM    
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MeSH Terms
Follow-Up Studies
Intraoperative Period
Lymph Node Excision
Neoplasm Invasiveness
Neoplasm Staging
Ovarian Neoplasms / diagnosis*,  pathology,  surgery
Physical Examination

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