Document Detail


Diagnosis and staging of gallbladder carcinoma. Evaluation with dynamic MR imaging.
MedLine Citation:
PMID:  11983470     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study is to determine the ability of dynamic magnetic resonance imaging (MRI) in the diagnosis and staging of gallbladder cancer (GBC). Images of dynamic MRI of hepatobiliary system combined with MR cholangiography (MRC) of 18 patients with pathologically proved gallbladder cancer were correlated with pathological and operative findings. Focal or diffuse wall thickening was present in 10 patients. In five patients, the tumor appeared as a fungating or intramural mass. A tumor replacing the gallbladder was found in two patients and a small cancer in cystic duct in one patient. The tumor featured early and irregular enhancement, which persisted throughout the dynamic study. Metastatic nodes were found by surgicopathology in 13 patients and were depicted by the dynamic MRI in 11 patients. Local invasion to liver was found by surgery in 12 patients and correctly detected by MRI in 11 patients. MRI detected duodenum invasion in three out of six patients and none of the three cases with omental metastasis. In conclusion, dynamic MRI is useful and reliable in staging of advanced gallbladder cancer. MRI combined with MRC is sensitive in detection of obstructive jaundice, liver invasion as well as liver and lymph nodes metastasis. It is more difficult to delineate the invasion to duodenum and omental metastasis by MRI.
Authors:
Jeng-Hwei Tseng; Yung-Liang Wan; Chien-Fu Hung; Koon-Kwan Ng; Kuang-Tse Pan; Andy Shau-Bin Chou; Nai-Jen Liu
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical imaging     Volume:  26     ISSN:  0899-7071     ISO Abbreviation:  Clin Imaging     Publication Date:    2002 May-Jun
Date Detail:
Created Date:  2002-05-01     Completed Date:  2002-07-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8911831     Medline TA:  Clin Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  177-82     Citation Subset:  IM    
Affiliation:
First Department of Diagnostic Radiology, Chang-Gung Memorial Hospital at Linkou, College of Medicine and School of Medical Technology, Chang-Gung University, 5 Fu-Hsing Street, Kwei-Shan, Taipei, Taiwan, ROC.
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MeSH Terms
Descriptor/Qualifier:
Aged
Carcinoma / diagnosis*,  pathology
Female
Gallbladder Neoplasms / diagnosis*,  pathology
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Neoplasm Staging

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