| Diagnosis of myocardial infarction by serum isoenzyme analysis. | |
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MedLine Citation:
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PMID: 324344 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Serial monitoring of the serum isoenzyme patterns of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) in patients suspected of acute myocardial infarction has become a highly sensitive and specific diagnostic method. The predictable evolution of isoenzyme patterns following infarction permits diagnosis and recognition of early stages, recovery stages and extension of infarction in the individual. Usual therapeutic and resuscitative manipulations do not interfere with evaluation of patients with angina or following cardiopulmonary arrest without infarction. Despite significant elevations of serum enzyme levels following general and cardiac operative procedures, the occurrence of myocardial necrosis in the surgical population can be recognized by detection of the specific CPK-MB isoenzyme. |
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Authors:
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C R Roe |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Annals of clinical and laboratory science Volume: 7 ISSN: 0091-7370 ISO Abbreviation: Ann. Clin. Lab. Sci. Publication Date: 1977 May-Jun |
Date Detail:
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Created Date: 1977-06-22 Completed Date: 1977-06-22 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0410247 Medline TA: Ann Clin Lab Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 201-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Clinical Enzyme Tests Creatine Kinase / blood* Electrocardiography Humans Isoenzymes / blood* L-Lactate Dehydrogenase / blood* Myocardial Infarction / blood, diagnosis*, enzymology |
| Chemical | |
Reg. No./Substance:
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0/Isoenzymes; EC 1.1.1.27/L-Lactate Dehydrogenase; EC 2.7.3.2/Creatine Kinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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