Document Detail


Diagnosis of megacystis-microcolon intestinal hypoperistalsis syndrome with aplastic desmosis in adulthood: a case report.
MedLine Citation:
PMID:  18334881     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Megacystis-microcolon intestinal hypoperistalsis syndrome (MMHIS or Berdon syndrome) is an autosomal-recessive disorder characterized by chronic intestinal obstruction. Although the disease is often diagnosed in female infants we describe a man with late diagnosis in adulthood. Our patient presented soon after birth with intestinal obstruction and developed short bowel syndrome after multiple intestinal resections. Of note, the connective tissue net within the muscle layers of the intestinal wall was absent ('aplastic desmosis'). This case illustrates the variable clinical features of MMHIS and aplastic desmosis, which might delay the correct diagnosis of a severe disorder.
Authors:
Jonel Trebicka; Erwin Biecker; Frank Gruenhage; Manfred Stolte; William A Meier-Ruge; Tilman Sauerbruch; Frank Lammert
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  20     ISSN:  0954-691X     ISO Abbreviation:  Eur J Gastroenterol Hepatol     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-12     Completed Date:  2008-07-24     Revised Date:  2009-10-16    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  353-5     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Bonn, Germany. jonel.trebicka@ukb.uni-bonn.de
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple* / surgery,  therapy,  ultrasonography
Adult
Colonic Diseases / etiology*,  surgery,  ultrasonography
Connective Tissue / abnormalities*
Enteral Nutrition
Humans
Intestinal Obstruction / etiology*,  surgery,  ultrasonography
Male
Peristalsis*
Short Bowel Syndrome / etiology*
Syndrome
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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