Document Detail


Diagnosis and management of pancreatic carcinoma during pregnancy.
MedLine Citation:
PMID:  20664439     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Acute, persistent abdominal pain due to ruptured pancreatic carcinoma and perforated stomach is extremely rare during pregnancy. CASE: We evaluated a woman at 34 weeks of gestation presenting with uterine contractions. Computed tomography scanning revealed a large retroperitoneal mass, and her blood carbohydrate antigen 19-9 level was elevated. Immediately after an emergency cesarean delivery, pancreatic cancer was detected, and pancreatoduodenectomy was performed. The patient underwent chemotherapy and remains disease-free at 2 years. CONCLUSION: Delayed diagnosis and treatment are associated with high morbidity of both neonate and mother in cases of pancreatic cancer during pregnancy. Computed tomography scanning and carbohydrate antigen 19-9 levels are useful for diagnosis, after which radical surgery should be performed immediately in late pregnancy.
Authors:
Toshimichi Onuma; Yoshio Yoshida; Takara Yamamoto; Fumikazu Kotsuji
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  116 Suppl 2     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-28     Completed Date:  2010-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  518-20     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, Fukui Aiiku Hospital, Fukui-city, Japan. i_love_music_andjp@yahoo.co.jp
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / complications,  diagnosis*,  surgery*
Adult
CA-19-9 Antigen / blood
Cesarean Section
Female
Humans
Pancreatic Neoplasms / complications,  diagnosis*,  surgery*
Pancreaticoduodenectomy
Pregnancy
Pregnancy Complications, Neoplastic / diagnosis*,  surgery*
Rupture, Spontaneous
Stomach Diseases / etiology,  surgery
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/CA-19-9 Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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