Document Detail

Diagnosis and management of distant recurrence in soft-tissue sarcomas.
MedLine Citation:
PMID:  8211195     Owner:  NLM     Status:  MEDLINE    
Understanding of the patterns of, and treatments for, metastatic disease from soft-tissue sarcoma is of vital importance in caring for these patients. Metastasis can occur independently of adequate local control. When metastasis occurs, it usually causes no symptoms. Thus, all patients with malignant soft-tissue sarcomas must be followed with a careful surveillance regimen. When metastasis is discovered, the overriding goals of surgical treatment must be total resection of all tumor with the minimal loss of functional lung tissue. Multiple subsequent resections may be needed for recurrent metastasis but the goals remain the same. Postoperative chemotherapy may be of benefit in eradicating residual micrometastases. With ongoing research and the advent of more effective and better-tolerated adjuvant therapies, we should continue to make progress obtaining better cure rates and longer duration of survival for these patients.
T E Gardner; J M Daly
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in oncology     Volume:  20     ISSN:  0093-7754     ISO Abbreviation:  Semin. Oncol.     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-11-15     Completed Date:  1993-11-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0420432     Medline TA:  Semin Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  456-61     Citation Subset:  IM    
Department of Surgery, University of Pennsylvania, School of Medicine, Philadelphia.
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MeSH Terms
Bone Neoplasms / radionuclide imaging
Chemotherapy, Adjuvant
Combined Modality Therapy
Liver Neoplasms / secondary
Lung Neoplasms / diagnosis,  secondary*,  surgery,  therapy
Magnetic Resonance Imaging
Patient Care Planning
Postoperative Care
Sarcoma / diagnosis,  secondary*,  therapy*
Survival Rate
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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