Document Detail

Diagnosis and management of clinical chorioamnionitis.
MedLine Citation:
PMID:  20569811     Owner:  NLM     Status:  MEDLINE    
Chorioamnionitis is a common complication of pregnancy associated with significant maternal, perinatal, and long-term adverse outcomes. Adverse maternal outcomes include postpartum infections and sepsis whereas adverse infant outcomes include stillbirth, premature birth, neonatal sepsis, chronic lung disease, and brain injury leading to cerebral palsy and other neurodevelopmental disabilities. Research in the past 2 decades has expanded understanding of the mechanistic links between intra-amniotic infection and preterm delivery as well as morbidities of preterm and term infants. Recent and ongoing clinical research into better methods for diagnosing, treating, and preventing chorioamnionitis is likely to have a substantial impact on short and long-term outcomes in the neonate.
Alan T N Tita; William W Andrews
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Clinics in perinatology     Volume:  37     ISSN:  1557-9840     ISO Abbreviation:  Clin Perinatol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-23     Completed Date:  2010-10-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  339-54     Citation Subset:  IM    
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine, University of Alabama at Birmingham, 619 19th South, Birmingham, AL 3524, USA.
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MeSH Terms
Chorioamnionitis / diagnosis*,  epidemiology,  microbiology,  therapy*
Diagnosis, Differential
Infant, Newborn
Pregnancy Complications, Infectious / diagnosis*,  epidemiology,  microbiology,  therapy*
Pregnancy Outcome
Risk Factors
Grant Support
5K12 HD01258-09/HD/NICHD NIH HHS; K12 HD001258-09/HD/NICHD NIH HHS

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