Document Detail

Diagnosis and invasive management of carotid atherosclerotic stenosis.
MedLine Citation:
PMID:  17605967     Owner:  NLM     Status:  MEDLINE    
Carotid atherosclerotic stenosis is a known risk factor for ischemic stroke. Methods for detecting stenosis and revascularization abound. The objective of this review was to summarize the evidence for diagnosing carotid artery stenosis and treating symptomatic or asymptomatic stenosis with endarterectomy or stenting. An Ovid MEDLINE search identified relevant original research published between 1990 and 2006. With acceptable surgical risk and patient life expectancy, carotid endarterectomy is clearly indicated for symptomatic stenosis of more than 70%. Carotid endarterectomy is also recommended for symptomatic stenosis of more than 50%, but the health impact is less compelling. The US Food and Drug Administration has approved several stents for a subset of patients with carotid stenosis. Randomized comparisons of endarterectomy vs stenting have been performed in average- and high-risk patients with asymptomatic and symptomatic carotid artery stenosis with mixed results.
James F Meschia; Thomas G Brott; Robert W Hobson
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Mayo Clinic proceedings     Volume:  82     ISSN:  0025-6196     ISO Abbreviation:  Mayo Clin. Proc.     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-07-03     Completed Date:  2007-08-02     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0405543     Medline TA:  Mayo Clin Proc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  851-8     Citation Subset:  AIM; IM    
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MeSH Terms
Carotid Stenosis* / diagnosis,  surgery
Endarterectomy, Carotid / adverse effects,  methods*
Evidence-Based Medicine
Randomized Controlled Trials as Topic
Grant Support
Comment In:
Mayo Clin Proc. 2007 Sep;82(9):1141; author reply 1141   [PMID:  17803868 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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