Document Detail

Diagnosis of fetal urinary tract malformations: prenatal management and postnatal outcome.
MedLine Citation:
PMID:  21744369     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To evaluate prenatal management and to define the criteria of gravity for accurate assessment of the renal and overall prognosis of fetuses presenting malformations of the urinary tract. METHODS: We carried out a retrospective study of 127 cases of urinary tract malformation. We carried out descriptive statistical and univariate analyses as a function of severity criteria and the outcome of pregnancy. RESULTS: One-third of fetuses presented associated extrarenal malformations and 10% of the karyotypes were abnormal. There were more abortions in case of decrease in amniotic fluid volume (p < 0.001), extent of renal damage (p < 0.05), presence of associated extrarenal malformations (p < 0.05), early diagnosis of the malformation (p < 0.001) and presence of chromosomal syndrome (p = 0.01). In our study, there was an excellent correlation between prenatal data and pathological findings for the fetus following abortions for medical reasons or obtained during the surveillance of live-born children. Fetal biochemistry made very little contribution. CONCLUSION: In cases of urinary tract malformation, this work confirms the need for regular and frequent ultrasound scans, checking for the echographic factors indicative of gravity and for adapted karyotyping. It also demonstrates that pluridisciplinary management is necessary for the prenatal evaluation of renal and overall fetal prognosis. Copyright © 2011 John Wiley & Sons, Ltd.
A Ryckewaert-D'Halluin; G Le Bouar; S Odent; J Milon; D D'Hervé; J Lucas; F Rouget; P Loget; P Poulain; E Le Gall; S Taque
Related Documents :
24642719 - Impact of a low glycemic index diet in pregnancy on markers of maternal and fetal metab...
15749509 - Obstetrical complications in gestational carrier pregnancies.
8990779 - Delayed delivery of surviving triplet after fetal reduction and spontaneous abortion.
24672159 - Should mild stimulation be the order of the day?
7268599 - Quintuplet gestation. a case report.
11665299 - Two cases with dichorionic diamniotic triplet pregnancy and early cord entanglement.
24527849 - Normal outcome of pregnancy with ongoing treatment with natalizumab.
12867289 - Non-invasive fetal sex determination using a conventional nested pcr analysis of fetal ...
9065139 - Prostanoid excretion in incipient singleton and twin pregnancies.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-11
Journal Detail:
Title:  Prenatal diagnosis     Volume:  -     ISSN:  1097-0223     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 John Wiley & Sons, Ltd.
Service de Médecine de l'enfant et de l'adolescent, CHU Rennes et Université Rennes 1, Rennes, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Second trimester biparietal diameter size and the risk of adverse pregnancy outcomes.
Next Document:  Corrections by melatonin of liver mitochondrial disorders under diabetes and acute intoxication in r...