Document Detail

Diagnosis and economic consequences of triclabendazole resistance in Fasciola hepatica in a sheep flock in south-east Scotland.
MedLine Citation:
PMID:  21493511     Owner:  NLM     Status:  MEDLINE    
Over the past decade, definite changes have been recorded in the regional prevalence, seasonality and severity of fasciolosis in the UK, related to increased rainfall, or localised flooding, prompting debate about the deleterious effects of climate change. As a consequence, effective management of fasciolosis has become problematic in areas where fluke traditionally exists, leading to serious loss of production in sheep and cattle. Meanwhile, in eastern districts, there have been unexpected outbreaks of disease, resulting in production losses and concerns about welfare. This case report describes the economic consequences of fasciolosis in a commercial sheep flock in south-east Scotland. The diagnosis and consequences of triclabendazole resistance are discussed, in the context of developing economically sustainable control strategies.
N D Sargison; P R Scott
Publication Detail:
Type:  Journal Article     Date:  2011-02-01
Journal Detail:
Title:  The Veterinary record     Volume:  168     ISSN:  2042-7670     ISO Abbreviation:  Vet. Rec.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-04-15     Completed Date:  2011-06-14     Revised Date:  2012-05-10    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  England    
Other Details:
Languages:  eng     Pagination:  159     Citation Subset:  IM    
Farm Animal Practice, Easter Bush Veterinary Centre, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian EH25 9RG.
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MeSH Terms
Anthelmintics / therapeutic use*
Benzimidazoles / therapeutic use*
Costs and Cost Analysis
Drug Resistance*
Fasciola hepatica / drug effects*
Fascioliasis / diagnosis,  drug therapy,  epidemiology,  veterinary*
Parasite Egg Count / veterinary
Parasitic Sensitivity Tests / veterinary
Sheep Diseases / diagnosis*,  drug therapy*,  epidemiology,  prevention & control
Treatment Outcome
Reg. No./Substance:
0/Anthelmintics; 0/Benzimidazoles; 68786-66-3/triclabendazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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