|Diagnosis of deep-vein thrombosis using an objective Doppler method.|
|PMID: 2190519 Owner: NLM Status: MEDLINE|
|STUDY OBJECTIVE: To determine the diagnostic criteria (phase I) and to assess the accuracy (phase II) of an objective Doppler-Valsalva pressure method as compared with contrast venography for the diagnosis of acute deep-leg-vein thrombosis in symptomatic outpatients. DESIGN: A two-phase prospective study in consecutive patients. Doppler ultrasound strip-chart recordings and venograms were independently analyzed by experienced observers. SETTING: Referral-based medical clinics at university medical centers. PATIENTS: One hundred and ten (phase I) and one hundred and fifty-five (phase II) patients who had clinically suspected venous thrombosis and were referred by their general practitioners were included. METHODS AND MEASUREMENTS: A normal Doppler test result was defined as a cyclic spontaneous signal (S-signal), a continuous S-signal with a Valsalva pressure of less than 6.5 mm Hg, or an absent S-signal with flow after cessation of the Valsalva maneuver. A continuous S-signal with a Valsalva pressure of 6.5 mm Hg or more or an absent S-signal without flow after cessation of the Valsalva maneuver were defined as abnormal test results. The accuracy indices for proximal vein thrombosis in phase II (155 patients; prevalence, 31%) were sensitivity, 91% (95% CI, 79% to 98%), and specificity, 99% (CI, 97% to 100%). All 3 patients with isolated calf-vein thrombosis had normal Doppler test results. CONCLUSIONS: The objective Doppler method is an accurate, reproducible, and simple method for detection of venous thrombosis in symptomatic outpatients.|
|A W Lensing; M M Levi; H R Büller; P Prandoni; M Vigo; G Agnelli; L Lupatelli; M V Huisman; J W ten Cate|
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|Type: Journal Article; Research Support, Non-U.S. Gov't|
|Title: Annals of internal medicine Volume: 113 ISSN: 0003-4819 ISO Abbreviation: Ann. Intern. Med. Publication Date: 1990 Jul|
|Created Date: 1990-07-12 Completed Date: 1990-07-12 Revised Date: 2006-11-15|
Medline Journal Info:
|Nlm Unique ID: 0372351 Medline TA: Ann Intern Med Country: UNITED STATES|
|Languages: eng Pagination: 9-13 Citation Subset: AIM; IM|
|Academic Medical Center, Amsterdam, The Netherlands.|
|APA/MLA Format Download EndNote Download BibTex|
Aged, 80 and over
Leg / blood supply
Predictive Value of Tests
Regional Blood Flow
Reproducibility of Results
Thrombophlebitis / diagnosis*
Ultrasonography / methods*
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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