| Diagnosis of coronary artery disease by exercise thallium-201 tomography in patients with a right ventricular pacemaker. | |
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MedLine Citation:
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PMID: 9137216 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: We sought to study the accuracy of exercise perfusion scintigraphy in patients with an implanted apical right ventricular pacemaker. BACKGROUND: The specificity of exercise perfusion scintigraphy is decreased in patients with a left bundle branch block. Patients with a permanent ventricular pacemaker have a similar conduction abnormality that may also potentially result in similar false positive perfusion defects. METHODS: One hundred five patients with a right ventricular pacemaker underwent exercise thallium-201 tomography and coronary angiography within 7 days of each other. Patients with a previous myocardial infarction were excluded. RESULTS: Patients were classified into four groups according to the agreement or disagreement between the thallium tomographic and coronary angiographic results. Only 8% of patients with normal results by both techniques were continuously paced during exercise, compared with 78% of patients with normal angiographic results but abnormal scintigraphic results. The mean defect size was 12% in the latter group. Most of the false positive defects were localized to the inferoposterior (71%), apical (50%) and inferoseptal (28%) walls. CONCLUSIONS: Patients who are paced in the right ventricular apex and who continue to be paced throughout exercise have a high incidence of false positive thallium-201 single-photon emission computed tomographic defects. |
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Authors:
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N M Lakkis; Z X He; M S Verani |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American College of Cardiology Volume: 29 ISSN: 0735-1097 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 1997 May |
Date Detail:
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Created Date: 1997-06-03 Completed Date: 1997-06-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1221-5 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Baylor College of Medicine, Houston, Texas, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Bundle-Branch Block / physiopathology, therapy Case-Control Studies Cohort Studies Coronary Angiography Coronary Disease / diagnosis, physiopathology, radionuclide imaging* Electrocardiography Exercise Test False Positive Reactions Female Heart / radionuclide imaging* Humans Male Pacemaker, Artificial* Predictive Value of Tests Sensitivity and Specificity Thallium Radioisotopes / diagnostic use Tomography, Emission-Computed, Single-Photon Ventricular Function, Left / physiology |
| Chemical | |
Reg. No./Substance:
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0/Thallium Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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