| Diagnosis of coronary artery disease by estimation of coronary sinus lactate. | |
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MedLine Citation:
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PMID: 708539 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In an attempt to assess the value of coronary sinus lactate estimation before and during atrial pacing for the diagnosis of obstructive coronary artery disease, 70 patients with angina were investigated in this way and by selective coronary arteriography. Thirty-five had radiologically normal coronary arteries and 35 had coronary artery disease. When the change in coronary arteriovenous lactate difference was less than 0.09 mmol/l (0.8 mg/100 ml) between the control and the peak atrial pacing sample, the coronary arteries were normal except in one patient who had distal disease of a single vessel. When the change was greater than 0.22 mmol/l (2.0 mg/100 ml) coronary artery disease was always found, and when the change was greater than 0.39 mmol/l (3.5 mg/100 ml) there was always disease of two or three vessels. Unfortunately, the presence or absence of coronary artery disease could not be predicted when the change fell between 0.09 and 0.22 mmol/l (0.8 and 2.0 mg/100 ml). Estimation of coronary sinus lactate before and during atrial pacing can thus frequently distinguish patients with normal coronary arteries from those with coronary artery disease. |
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Authors:
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G Jackson; L Atkinson; M Clark; B Crook; P Armstrong; S Oram |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British heart journal Volume: 40 ISSN: 0007-0769 ISO Abbreviation: Br Heart J Publication Date: 1978 Sep |
Date Detail:
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Created Date: 1979-01-24 Completed Date: 1979-01-24 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0370634 Medline TA: Br Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 979-83 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angina Pectoris / blood, diagnosis* Angiocardiography Cardiac Pacing, Artificial Coronary Disease / diagnosis* Coronary Vessels Electrocardiography Exercise Test Female Humans Lactates / blood* Lipids / blood Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Lactates; 0/Lipids |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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