Document Detail

Diagnosis of conjoined twins before 16 weeks' gestation: the 4-year experience of one medical center.
MedLine Citation:
PMID:  16170850     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Descriptions of the rarely occurring condition of conjoined twins are sparse. METHODS: We report a case series of four conjoined twin pregnancies diagnosed up to 16 weeks of gestation. One was in a quadruplet in vitro fertilization intracytoplasmic sperm injection (IVF-ICSI) pregnancy of cryopreserved embryos and the others were spontaneous conceptions. Three were thoracopagus and had increased nuchal translucency (NT) or big nuchal cysts and one was omphalopagus. RESULTS: All the three affected twin pregnancies were terminated by cervical dilatation and uterine evacuation. In another case, selective fetal reduction, shortly followed by embryo reduction to singleton was performed. Histological analysis of one case revealed dissimilar gender. No further cytogenetic or molecular studies were conducted by parental request. The pathophysiology of increased NT, subcutaneous edema or nuchal cysts in thoracopagus conjoined twins, the possible embryonic events that may lead to dizygotic conjoined twins and the clinical management of conjoined twins in sets of multiple gestation are discussed. CONCLUSIONS: The current case series illustrates that there are many problems related to this rare, but intriguing, accident of nature that still need to be overcome.
Ron Maymon; Sonia Mendelovic; Morey Schachter; Raphael Ron-El; Zwi Weinraub; Arie Herman
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  25     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-28     Completed Date:  2005-12-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  England    
Other Details:
Languages:  eng     Pagination:  839-43     Citation Subset:  IM    
Copyright Information:
2005 John Wiley & Sons, Ltd.
Department of Obstetrics and Gynecology, Tel-Aviv University, Tel-Aviv, Israel.
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MeSH Terms
Abortion, Induced
Diagnosis, Differential
Fertilization in Vitro
Pregnancy Trimester, First
Prenatal Diagnosis*
Sperm Injections, Intracytoplasmic
Twins, Conjoined*
Ultrasonography, Prenatal

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