Document Detail

Diagnosis of cardiac disease in pediatric end-stage renal disease.
MedLine Citation:
PMID:  20861193     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Cardiac disease is a significant cause of morbidity and mortality in children with end-stage renal disease (ESRD). This study aimed to report the frequency of cardiac disease diagnostic methods used in US pediatric maintenance hemodialysis patients.
METHODS: A cross-sectional analysis of all US pediatric (ages 0.7-18 years, n = 656) maintenance hemodialysis patients was performed using data from the Centers for Medicare and Medicaid Services ESRD Clinical Performance Measures Project. Clinical and laboratory information was collected in 2001. Results were analysed by age, sex, race, Hispanic ethnicity, dialysis duration, body mass index (BMI), primary ESRD cause and laboratory data.
RESULTS: Ninety-two percent of the patients had a cardiovascular risk factor (63% hypertension, 38% anemia, 11% BMI > 94th percentile, 63% serum phosphorus > 5.5 mg/dL and 55% calcium-phosphorus product ≥ 55 mg(2)/dL(2)). A diagnosis of cardiac disease was reported in 24% (n = 155) of all patients: left ventricular hypertrophy/enlargement 17%, congestive heart failure/pulmonary edema 8%, cardiomyopathy 2% and decreased left ventricular function 2%. Thirty-one percent of patients were not tested. Of those tested, the diagnostic methods used were chest X-rays in 60%, echocardiograms in 35% and electrocardiograms in 33%; left ventricular hypertrophy/enlargement was diagnosed using echocardiogram (72%), chest X-ray (20%) and electrocardiogram (15%).
CONCLUSIONS: Although 92% of patients had cardiovascular risk factors, an echocardiography was performed in only one-third of the patients. Our study raises the question of why echocardiography, considered the gold standard for cardiac disease diagnosis, has been infrequently used in pediatric maintenance dialysis patients, a high-risk patient population.
Blanche M Chavers; Craig A Solid; Alan Sinaiko; Frank X Daniels; Shu-Cheng Chen; Allan J Collins; Diane L Frankenfield; Charles A Herzog
Related Documents :
22438643 - Determination of levels of salivary iga subclasses in patients with minor recurrent aph...
7315333 - Cardiac involvement in juvenile amaurotic idiocy--a specific heart muscle disorder. his...
25294783 - Electrophysiologic substrate in congenital long qt syndrome: noninvasive mapping with e...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-09-22
Journal Detail:
Title:  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association     Volume:  26     ISSN:  1460-2385     ISO Abbreviation:  Nephrol. Dial. Transplant.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-02     Completed Date:  2011-09-27     Revised Date:  2013-05-27    
Medline Journal Info:
Nlm Unique ID:  8706402     Medline TA:  Nephrol Dial Transplant     Country:  England    
Other Details:
Languages:  eng     Pagination:  1640-5     Citation Subset:  IM    
Department of Pediatrics University of Minnesota Amplatz Children’s Hospital, Minneapolis, MN, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cardiovascular Diseases / diagnosis*,  etiology*
Child, Preschool
Cross-Sectional Studies
Follow-Up Studies
Kidney Failure, Chronic / complications*,  therapy
Renal Dialysis*
Risk Factors
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast can...
Next Document:  Unexplained sudden death in patients on the waiting list for renal transplantation.