| Diagnosis of burn depth using laser-induced indocyanine green fluorescence: a preliminary clinical trial. | |
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MedLine Citation:
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PMID: 11348745 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Clinical assessment of burn depth is frequently inaccurate. In order to effectively plan the treatment of burn wounds, an accurate diagnosis of burn depth is desirable. A new method for evaluating the depth of burns by imaging the blood flow through the burned tissue using fluorescence from intravenously injected indocyanine green (ICG) dye illuminated with a 785-nm, near-infrared diode laser array was evaluated. Nine patients and 15 individual burn sites were studied. Five sites were classified by the ICG study as superficial second degree, four were deep-dermal second degree, and six were third degree. Etiology of the injuries included flame, contact burns, and scalds. The date postburn of the study ranged from 1 to 11 days. In all cases, the relative fluorescence levels (e.g. superficial second-degree burns yielded relatively bright fluorescence, third-degree burns appeared much darker than surrounding normal skin) were found to correlate well with actual burn depth as determined by histologic examination of biopsies and intraoperative clinical assessment. |
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Authors:
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J M Still; E J Law; K G Klavuhn; T C Island; J Z Holtz |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Burns : journal of the International Society for Burn Injuries Volume: 27 ISSN: 0305-4179 ISO Abbreviation: Burns Publication Date: 2001 Jun |
Date Detail:
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Created Date: 2001-05-11 Completed Date: 2001-07-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8913178 Medline TA: Burns Country: England |
Other Details:
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Languages: eng Pagination: 364-71 Citation Subset: IM |
Affiliation:
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The Joseph M. Still Burn Center, Columbia-Augusta Medical Center, Augusta, GA, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Burns / pathology*, physiopathology Coloring Agents / diagnostic use Fluorescence Humans Indocyanine Green / diagnostic use* Lasers / diagnostic use* Male Middle Aged Skin / blood supply |
| Chemical | |
Reg. No./Substance:
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0/Coloring Agents; 3599-32-4/Indocyanine Green |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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