| Diagnosis of breast cancer with multidetector computed tomography: analysis of optimal delay time after contrast media injection. | |
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MedLine Citation:
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PMID: 20122514 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The aim of this study was to investigate the optimal delay time after a contrast media injection for multidetector computed tomography (MD-CT) images in the diagnosis of breast cancer patients. MATERIALS AND METHODS: Thirty-one patients who underwent MD-CT for their preoperative examination and who had postoperatively confirmed pathology were enrolled. Four-phase images of dynamic contrast enhanced study were acquired using four-detector MDCT. All cases were mammographically classified into two groups according to BI-RADS: nondense and dense groups. The CT value of the background mammary gland, background breast enhancement (BBE), and tumor-background mammary gland contrast (TBC) were compared between the two groups. RESULTS: The CT value of the dense group was significantly higher than that of the nondense group in all phases. BBE in both nondense and dense groups showed no significant differences in any of the phases. In the nondense group, TBC was significantly higher in both the second and the third phases than in the first phase, while in the dense group, TBC was significantly higher in the second phase than in the first and third phases. CONCLUSION: The optimal delay time to depict breast cancer is 80 s after a contrast media injection, regardless of the density level of the background mammary gland. |
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Authors:
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Seiko Kuroki-Suzuki; Yoshifumi Kuroki; Tsutomu Ishikawa; Hideya Takeo; Noriyuki Moriyama |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical imaging Volume: 34 ISSN: 1873-4499 ISO Abbreviation: Clin Imaging Publication Date: 2010 Jan-Feb |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-04-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8911831 Medline TA: Clin Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 14-9 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104-0045, Japan. skuroki@ncc.go.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Breast Neoplasms / radiography* Contrast Media / administration & dosage* Female Humans Injections, Intravenous Iodine / administration & dosage*, diagnostic use* Mammography / methods* Middle Aged Radiographic Image Enhancement / methods Radiographic Image Interpretation, Computer-Assisted / methods* Reproducibility of Results Sensitivity and Specificity Time Factors Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 7553-56-2/Iodine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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