Document Detail


Diagnosis of brain death using two-phase spiral CT.
MedLine Citation:
PMID:  9576648     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The purpose of this study was to determine the utility of spiral CT in the diagnosis of brain death. METHODS: Spiral CT was evaluated prospectively in 14 brain-dead patients and in 11 healthy subjects. A two-phase protocol was used. Twenty seconds after intravenous injection of a nonionic iodinized contrast medium, the CT table was drawn through the gantry at a rate of 10 mm/s while scanning was in progress. The second scanning phase was started automatically a mean of 54 seconds later, using the same parameters. Opacification or absence of opacification of carotid, vertebral, and basilar arteries and intracerebral veins was ascertained for each image in both phases. The diagnosis of brain death was confirmed by elecroencephalography (n = 7), angiography (n = 5), or both (n = 2). Statistical analysis with the Fisher exact test enabled us to compare the brain-dead patients with the healthy control subjects. RESULTS: In brain death, the pericallosal and terminal arteries of the cortex did not opacify during the two phases of spiral CT, whereas the superficial temporal arteries were always visible. The internal cerebral veins, the great cerebral vein, and the straight sinus did not opacify, whereas the superior ophthalmic veins were visible on both sides 13 times. For each vessel type, specificity was 100% for nonvascular opacification criteria on the right and left sides. CONCLUSION: Two-phase spiral CT can demonstrate the absence of intracerebral blood flow in brain death.
Authors:
B Dupas; M Gayet-Delacroix; D Villers; D Antonioli; M F Veccherini; J P Soulillou
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  19     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-06-19     Completed Date:  1998-06-19     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  641-7     Citation Subset:  IM    
Affiliation:
Service de Radiologie et d'Imagerie Médicale, Centre Hospitalier Universitaire de Nantes, France.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Brain Death / radiography*
Cerebral Angiography
Child
Electroencephalography
Female
Humans
Male
Middle Aged
Subtraction Technique
Tomography, X-Ray Computed / methods*
Comments/Corrections
Comment In:
AJNR Am J Neuroradiol. 1998 Apr;19(4):796   [PMID:  9576677 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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